Metastasis is a major problem in cancer and accounts for about 90% of cancer deaths. Treating metastasis remains the primary goal of current cancer research. Although new treatment drugs are promising, drug resistance hinders their durable efficacy. Our primary research interest is the complex molecular and genetic mechanisms associated with cancer progression to the metastatic state and drug resistance in order to identify candidate molecular targets or signaling pathways relevant to underlying mechanisms, clinical diagnosis, therapeutic utility, and prevention. Our goal is to find new drugs to eliminate or reduce the metastatic burden and overcome drug resistance to improve cancer therapy outcomes. Our current studies focus on the interaction between the tumor cell and microenvironment in tumor metastasis, the molecular mechanism associated with double resistance to BRAF/MEK inhibition in melanoma.
We are seeking a highly motivated and dedicated post-baccalaureate fellow with a strong interest in these metastatic projects.
The candidate should be self-motivated, enthusiastic, and have excellent organizational skills with a biology-related background (GPA >3.5). We prefer candidates with experience in cell/tissue culture.
We will consider candidates who are seeking a temporary position (one-year commitment) before applying to graduate and/or medical school.
Qualifications and Job Details
Required and Preferred Skills
Basic cellular and molecular biology techniques.
Tissue culture and biochemical techniques.
About the NCI Center for Cancer Research
The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.
Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.