Director - Chromatin Biology, Gene Expression

Date Posted
Position is with
Name of Hiring Official/Investigator

Job Description

The National Cancer Institute (NCI) is seeking an outstanding, internationally recognized, and visionary leader in the field of chromatin biology to direct an internationally recognized research program in the current Laboratory of Receptor Biology and Gene Expression (LRBGE) in the NCI Center for Cancer Research (CCR). This position is part of the National Institutes of Health’s (NIH) world-class Intramural Research Program and is equivalent to a tenured academic department chair.

The LRBGE is a world leader in elucidating fundamental properties of gene expression and genome organization, including 3D genome organization, centromere biology, gene and transcription factor dynamics, RNA splicing and RNA modifications. LRBGE comprises six principal investigators and includes core facilities for advanced light imaging and high-throughput imaging. 

In addition to heading the LRBGE, the Director will also be tenure eligible at the NIH and will lead their own individual world-class research program, supported by generous, stable resources, including access to a wide range of NCI technology platforms and interdisciplinary collaborations within NCI, as well as at NIH and its Clinical Center. NCI intramural investigators are not expected to support their research via grants.

Qualifications and Job Details

Degree Required
Ph.D. or equivalent
M.D. or equivalent
Job Location
Appointment Type
Government Position (Salary commensurate with experience)
Work Schedule
Full-time (Hybrid)
US Citizenship not required - (ie, permanent resident, visa)

Required and Preferred Skills

Required Skills

The successful candidate will be an exceptional leader in the chromosome biology field with a broad vision who will embrace the rapidly changing landscape of the field. The selected individual will have the opportunity to build an impactful research program relevant to cancer research by setting the scientific direction and vision of the program. The Director will define the overall scientific strategy and direction of the program and will identify new research opportunities, including recruitment of faculty, management of laboratory resources, and mentoring and training. The incoming Director must have a strong, clearly articulated commitment to diversity, equity, and inclusion.

The successful candidate must hold a Ph.D., M.D./Ph.D., or equivalent. Additionally, the successful candidate must have an established record in the field, demonstrated leadership ability, and proven effectiveness in mentoring. This position is located at the NIH campus in Bethesda, M.D. and requires significant in-person on-site presence.

About the NCI Center for Cancer Research

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.


Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.

How to Apply
  • CV/Resume
  • Statement of Research Goals
  • Cover Letter
  • Diversity Statement
Additional Application Information

Salary will be commensurate with experience. A full civil service package of benefits (including health insurance, life insurance, and retirement) is available. Candidates may be U.S. citizens, U.S. permanent residents, or eligible for a visa that will enable work in the United States. This position is subject to a background investigation.

Interested candidates should submit the following materials:

  • A letter of interest, including a career synopsis
  • A forward-looking statement of research interests and vision statement for the LRBGE (four-page limit)
  • A current curriculum vitae and complete bibliography
  • A diversity statement describing your track record of and commitment to promoting diversity, equity, and inclusion in biomedical research and/or medicine, including but not limited to successful recruitment and/or mentorship of trainees from historically underrepresented groups, participation on committees and in programs/initiatives addressing issues of diversity and inclusion, and your future plans for addressing diversity and inclusion as a Laboratory Director (one-page limit)

Applications should be submitted electronically to and will be accepted until the position is filled. Review of applications will begin approximately October 1, 2023.

For more information, please contact Lori Holliday, CCR Faculty Recruitment Coordinator at

Contact Information
Contact Name
Lori Holliday
E-mail Address
DHHS, NIH and NCI are equal opportunity employers. The NCI and CCR are deeply committed to diversity of thought, equity and inclusion and encourage applications from qualified women, underrepresented minorities and individuals with disabilities.