Alexandra S. Zimmer, M.D.

Alexandra S. Zimmer, M.D.
Assistant Research Physician
Women's Malignancies Branch
Clinical Director, Women's Malignancies Branch

Dr. Zimmer is an Assistant Research Physician with the Women's Malignancies Branch. Her main clinical and research interest is in breast cancer metastatic disease. More specifically, she is interested in developing translational clinical trials that target the study of metastasis prevention therapy and treatment of brain metastasis. As Clinical Director, Dr. Zimmer oversees the Branch's clinical operations.

Areas of Expertise
1. Breast cancer 2. Brain metastases 3. Translational clinical trials 4. Metastasis prevention

Contact Info

Alexandra S. Zimmer, M.D.
Center for Cancer Research
National Cancer Institute
Building 10, Room 2N50A
Bethesda, MD 20892
Ph: 240-760-6132
alexandra.zimmer@nih.gov
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Dr. Zimmer focuses her research mainly in metastatic breast cancer and ovarian cancer, with a special interest in brain metastases and development of translational clinical trials.
Scientific Focus Areas:
Cancer Biology, Clinical Research, Molecular Biology and Biochemistry

Selected Key Publications

  1. Meaningful prevention of breast cancer metastasis: Candidate therapeutics, preclinical validation, and clinical trial concerns.
    Zimmer AS and Steeg PS
    J. Mol. Med.. 93: 13-29, 2015. [ Journal Article ]
  2. A European Organization for Research and Treatment of Cancer phase I study of lapatinib and docetaxel as neoadjuvant treatment for human epidermal growth factor receptor 2 (HER2) positive locally-advanced/inflammatory or large operable breast cancer.
    Bonnefoi H, Zaman K, Debled M, Fiche M, Fournier M, Nobahar M, Pierga JY, Koch KM, Bartlett J, Zimmer A, Marreaud S, Bogaerts J, Cameron D
    Eur. J. Cancer. 49(2): 281-289, 2013. [ Journal Article ]
  3. HER-2 Targeting Agents and Antiangiogenic Therapy: Evolution of Adjuvant Therapy in Breast Cancer.
    Sinclair S, Zimmer AS, Swain SM
    In: ASCO Educational Book. 3-10, 2009. [ Book Chapter ]
  4. Comments on: Molecular determinants of the inflammatory breast cancer phenotype, by Houchens NW and Merajver SD.
    Zimmer AS, Swain SM
    J. Oncol.. 22(14): 1566-1576, 2013. [ Journal Article ]

Dr. Zimmer received her M.D. from the Universidade Federal of Rio Grande do Sul, Brazil and was fully trained in Internal Medicine and Clinical Oncology in Brazil, before moving to Brussels, Belgium to complete a Clinical Trials Development Fellowship with the Breast Cancer Group of the European Organization for Research and Treatment of Cancer (EORTC). After completion of that fellowship, Dr. Zimmer moved to the USA and repeated her residency in Internal Medicine at Washington Hospital Center, Washington, DC, and Clinical Oncology Fellowship at NIH. During her training, Dr. Zimmer focused her research mainly in metastatic breast cancer and ovarian cancer, with a special interest in brain metastases and development of translational clinical trials.

Name Position
Irene Ekwede R.N. Research Nurse
Mireya Gomez Patient Care Coordinator (Contr.)
Nicole D. Houston R.N. Research Nurse
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The Latest in Research for Advanced Breast Cancer: Facebook Live Event