Alexandra S. Zimmer, M.D.
Dr. Zimmer is an Assistant Research Physician with the Women's Malignancies Branch. Her main clinical and research interest is in breast cancer metastatic disease. More specifically, she is interested in developing translational clinical trials that target the study of metastasis prevention therapy and treatment of brain metastasis. As Clinical Director, Dr. Zimmer oversees the Branch's clinical operations.
A Phase 2 Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial CarcinomaOpen - RecruitingNCI Protocol ID NCI-18-C-0034Investigator Alexandra S. Zimmer, M.D.Share this trial: Referral Contacts
Contact Name Phone Number Nicole Houston 240 760-6127
Phase I/II Study of T-DM1 alone versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic RadiosurgeryOpen - RecruitingNCI Protocol ID NCI-17-C-0115Investigator Alexandra S. Zimmer, M.D.Share this trial: Referral Contacts
Contact Name Phone Number Nicole Houston 240-760-6127
Selected Key Publications
Meaningful prevention of breast cancer metastasis: Candidate therapeutics, preclinical validation, and clinical trial concerns.J. Mol. Med.. 93: 13-29, 2015. [ Journal Article ]
A European Organization for Research and Treatment of Cancer phase I study of lapatinib and docetaxel as neoadjuvant treatment for human epidermal growth factor receptor 2 (HER2) positive locally-advanced/inflammatory or large operable breast cancer.Eur. J. Cancer. 49(2): 281-289, 2013. [ Journal Article ]
HER-2 Targeting Agents and Antiangiogenic Therapy: Evolution of Adjuvant Therapy in Breast Cancer.In: ASCO Educational Book. 3-10, 2009. [ Book Chapter ]
Comments on: Molecular determinants of the inflammatory breast cancer phenotype, by Houchens NW and Merajver SD.J. Oncol.. 22(14): 1566-1576, 2013. [ Journal Article ]
Dr. Zimmer received her M.D. from the Universidade Federal of Rio Grande do Sul, Brazil and was fully trained in Internal Medicine and Clinical Oncology in Brazil, before moving to Brussels, Belgium to complete a Clinical Trials Development Fellowship with the Breast Cancer Group of the European Organization for Research and Treatment of Cancer (EORTC). After completion of that fellowship, Dr. Zimmer moved to the USA and repeated her residency in Internal Medicine at Washington Hospital Center, Washington, DC, and Clinical Oncology Fellowship at NIH. During her training, Dr. Zimmer focused her research mainly in metastatic breast cancer and ovarian cancer, with a special interest in brain metastases and development of translational clinical trials.
|Irene Ekwede R.N.||Research Nurse|
|Mireya Gomez||Patient Care Coordinator (Contr.)|
|Nicole D. Houston R.N.||Research Nurse|