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Uma T. Shankavaram, Ph.D.

Uma T. Shankavaram, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Radiation Oncology Branch

RESEARCH SUMMARY

Dr. Shankavaram manages the Radiation Oncology Branch’s Microarray Core Facility (MCF), which provides services and access to new technologies to investigators from NCI and other NIH institutes. The MCF offers special expertise in gene expression array hybridization, statistical analysis, genetics/genomics, and technical support.

  • Gene Expression Arrays:   gene chip processing of cDNA and Affymetrix arrays
  • Boinformatics Analysis:  consultation with scientists prior to experiments, analysis of high-throughput sequencing, gene expression, metabolomics, proteomics and other biological data, including functional and gene set enrichment analysis
  • Application Development:  develops custom applications to enhance research through web applications for data analysis, databases, visualization, and custom analysis tools
  • Training:  informal training to assist researchers in using computational tools

Areas of Expertise

Bioinformatics
Genetics
Genomics
High-throughput Data Analysis
Statistical And Computational Methods
Web Application Development

Publications

Selected Recent Publications

SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex.

Rasti G, Becker M, Vazquez BN, Espinosa-Alcantud M, Fernández-Duran I, Gámez-García A, Ianni A, Gonzalez J, Bosch-Presegué L, Marazuela-Duque A, Guitart-Solanes A, Segura-Bayona S, Bech-Serra JJ, Scher M, Serrano L, Shankavaram U, Erdjument-Bromage H, Tempst P, Reinberg D, Olivella M, Stracker TH, de la Torre C, Vaquero A.
Nucleic Acids Res. 51(13): 6754-6769, 2023.
Full-Text Article
[ Journal Article ]

Immune signature of pheochromocytoma and paraganglioma in context of neuroendocrine neoplasms associated with prognosis

Ghosal S, Vanova KH, Uher O, Das S, Patel M, Meuter L, Huynh TT, Jha A, Talvacchio S, Knue M, Prodanov T, Zeiger MA, Nilubol N, Taieb D, Crona J, Shankavaram UT, Pacak K.
Endocrine. 79(1): 171-179, 2023.
Full-Text Article
[ Journal Article ]

Glioma-BioDP: database for visualization of molecular profiles to improve prognosis of brain cancer

Deng X, Das S, Kaur H, Wilson E, Camphausen K, Shankavaram U.
BMC Med Genomics. 16(1): 168, 2023.
Full-Text Article
[ Journal Article ]

Glioblastoma cells have increased capacity to repair radiation-induced DNA damage after migration to the olfactory bulb

Degorre C, Sutton IC, Lehman SL, Shankavaram UT, Camphausen K, Tofilon PJ.
Cancer Cell Int. 22(1): 389, 2022.
Full-Text Article
[ Journal Article ]

Bowel and Bladder Reproducibility in Image Guided Radiation Therapy for Prostate Cancer: Results of a Patterns of Practice Survey

Rowe LS, Mandia JJ, Salerno KE, Shankavaram UT, Das S, Escorcia FE, Ning H, Citrin DE.
Adv Radiat Oncol. 7(5): 100902, 2022.
Full-Text Article
[ Journal Article ]

Team

Research Fellow
Shaoli Das, Ph.D.
Programmer Analyst III (Contr.)
Xiang Deng