R. Taylor Ripley, M.D.

R. Taylor Ripley, M.D.

Dr. R. Taylor Ripley's research focus is in thoracic surgical oncology and specifically in esophageal cancer.  His other expertise includes lung cancer, mesothelioma, thymic malignancies, pulmonary metastasis, and minimally-invasive thoracic surgery.  He is developing a laboratory effort in the metabolomic profiles of esophageal cancer.

For patient information:

Referral line: 301-451-1233

Colleen Bond, Thoracic Surgery Nurse Practitioner
Colleen.Bond@nih.gov; 301-435-4012

Tricia Kunst, Research Nurse
kunstt@nih.gov; 301-402-4399

Areas of Expertise
1) esophageal cancer, 2) lung cancer, 3) mesothelioma, 4) pulmonary metastasectomy, 5) minimally-invasive thoracic surgery

Contact Info

R. Taylor Ripley, M.D.
Center for Cancer Research
National Cancer Institute
Building 10, Room 4-3952
Bethesda, MD 20892
Ph: 301-435-7504

My clinical and research interests are in the treatment of esophageal cancer.  We are evaluating the effects of environmental exposure of esophageal adenocarcinoma to determine whether epigenetic and metabolomic targets can be identified.  Specifically, the efforts will focus on the activation of oncogenes and the silencing of tumor suppressors by environmental stimuli that promote tumor growth and treatment resistance.

Scientific Focus Areas:
Cancer Biology, Cell Biology, Clinical Research
View Dr. Ripley's PubMed Summary.

Selected Recent Publications

  1. Ripley RT, McMillan RR, Sima CS, Hasan SM, Ahmad U, Lou F, Jones DR, Rusch VW, Rizk NP, and Huang J.
    Ann Thorac Surg. 98: 986-74, 2014. [ Journal Article ]
  2. Ripley RT, Rusch VW.
    Thorac Surg Clin. 23: 273-85, 2013. [ Journal Article ]
  3. Zhang M, Mathur A, Zhang Y, Xi S, Atay S, Hong JA, Datrice N, Upham T, Kemp CD, Ripley RT, Wiegand G, Avital I, Fetsch P, Mani H, Zlott D, Robey R, Bates SE, Li X, Rao M, Schrump DS.
    Cancer Res. 72: 4178-92, 2012. [ Journal Article ]
  4. Kemp CD, Ripley RT, Mathur A, Steinberg SM, Nguyen DM, Fojo T, and Schrump DS.
    Ann Thorac Surg. 92: 1195-200, 2011. [ Journal Article ]
  5. Pre-treatment dysphagia in esophageal cancer may eliminate the need for staging by endoscopic.
    Ripley RT, Sarkaria I, Grosser R, Bains M, Jones DR, Adusumilli P, Huang J, Finley D, Sima CS, Rusch V, and Rizk NP.
    Ann Thorac Surg. in press: 2015. [ Journal Article ]

Dr. Ripley trained in thoracic surgery at Memorial Sloan-Kettering Cancer Center with a focus in thoracic surgical oncology.  Prior to thoracic surgery, he completed the Surgical Oncology Fellowship in the Surgery Branch, NCI, and trained in general surgery at the University of Colorado.  He earned a medical doctorate in 2004 from Vanderbilt University.

Name Position
Colleen D. Bond A.C.N.P. Nurse Practitioner
Kate Brown Ph.D. Postdoctoral Fellow (Visiting)
Claudia Espinoza Patient Care Coordinator (Contr)
Tania Guerrero Amparo Data Manager (Contr)
Yuan Xu Ph.D. Postdoctoral Fellow (Visiting)