R. Taylor Ripley, M.D.
Dr. R. Taylor Ripley's research focus is in thoracic surgical oncology and specifically in esophageal cancer. His other expertise includes lung cancer, mesothelioma, thymic malignancies, pulmonary metastasis, and minimally-invasive thoracic surgery. He is developing a laboratory effort in the metabolomic profiles of esophageal cancer.
For patient information:
Referral line: 301-451-1233
Colleen Bond, Thoracic Surgery Nurse Practitioner
Tricia Kunst, Research Nurse
Metabolomic and BH3 Profiling of Esophageal Cancers: Identification of Novel Assessment Methods of Treatment Response for Precision TherapyOpen - RecruitingNCI Protocol ID NCI-17-C-0135Investigator R. Taylor Ripley, M.D.Share this trial: Referral Contacts
Contact Name Phone Number Cara M. Kenney 240-760-6233
My clinical and research interests are in the treatment of esophageal cancer. We are evaluating the effects of environmental exposure of esophageal adenocarcinoma to determine whether epigenetic and metabolomic targets can be identified. Specifically, the efforts will focus on the activation of oncogenes and the silencing of tumor suppressors by environmental stimuli that promote tumor growth and treatment resistance.
Selected Recent Publications
Second primary lung cancers: smokers versus non-smokers after resection of stage I lung adenocarcinoma.Ann Thorac Surg. 98: 986-74, 2014. [ Journal Article ]
Role of induction therapy: surgical resection of non-small cell lung cancer after induction therapy.Thorac Surg Clin. 23: 273-85, 2013. [ Journal Article ]
Mithramycin represses basal and cigarette smoke-induced expression of ABCG2 and inhibits stem cell signaling in lung and esophageal cancer cells.Cancer Res. 72: 4178-92, 2012. [ Journal Article ]
Pulmonary resection for metastatic adrenocortical carcinoma: the National Cancer Institute experience.Ann Thorac Surg. 92: 1195-200, 2011. [ Journal Article ]
Pre-treatment dysphagia in esophageal cancer may eliminate the need for staging by endoscopic.Ann Thorac Surg. in press: 2015. [ Journal Article ]
Dr. Ripley trained in thoracic surgery at Memorial Sloan-Kettering Cancer Center with a focus in thoracic surgical oncology. Prior to thoracic surgery, he completed the Surgical Oncology Fellowship in the Surgery Branch, NCI, and trained in general surgery at the University of Colorado. He earned a medical doctorate in 2004 from Vanderbilt University.
|Colleen D. Bond A.C.N.P.||Nurse Practitioner|
|Kate Brown Ph.D.||Postdoctoral Fellow (Visiting)|
|Claudia Espinoza||Patient Care Coordinator (Contr)|
|Tania Guerrero Amparo||Data Manager (Contr)|
|Yuan Xu Ph.D.||Postdoctoral Fellow (Visiting)|