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Haobin Chen, M.D., Ph.D.

Haobin Chen, M.D., Ph.D.

  • Center for Cancer Research
  • National Cancer Institute
Thoracic Surgery Branch

RESEARCH SUMMARY

Dr. Chen's research focuses on developing novel epigenetic therapies for the treatment of small cell lung cancer. He is board-certified in internal medicine and medical oncology.

Areas of Expertise

1) small cell lung cancer 2) epigenetics 3) molecular biology

Information for Patients

Learn more about our clinical trials and the highly specialized care teams that lead them. 

Publications

Selected Key Publications

Molecular Subtypes of Primary SCLC Tumors and Their Associations With Neuroendocrine and Therapeutic Markers

Qu S, Fetsch P, Thomas A, Pommier Y, Schrump DS, Miettinen MM, Chen H*
J Thorac Oncol . Online ahead of Print: 2021. [ Journal Article ]

Genotype of CDC73 Germline Mutation Determines Risk of Parathyroid Cancer

Li Y*, Zhang J, Adikaram PR, Welch J, Guan B, Weinstein LS, Chen H*, Simonds WF*
Endocr-relat Cancer . 27(9): 483-494, 2020. [ Journal Article ]

Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors

Thomas A, Redon CE, Sciuto L, Padiernos E, Ji J, Lee MJ, Yuno A, Lee S, Zhang Y, Tran L, Yutzy W, Rajan A, Guha U, Chen H, Hassan R, Alewine CC, Szabo E, Bates SE, Kinders RJ, Steinberg SM, Doroshow JH, Aladjem MI, Trepel JB, Pommier Y
J Clin Oncol.. 36(16): 1594-1602, 2018. [ Journal Article ]

Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers

Chen H, Giri NC, Zhang R, Yamane K, Zhang Y, Maroney M, Costa M
J Biol Chem. 285(10):: 7374-83, 2010. [ Journal Article ]

Hypoxia and nickel inhibit histone demethylase JMJD1A and repress Spry2 expression in human bronchial epithelial BEAS-2B cells

Chen H, Zhang R, Kluz T, Costa M.
Carcinogenesis. 31: 2136-2144, 2010. [ Journal Article ]

Job Vacancies

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Alumni

Lisa Gesumaria
Lisa Gesumaria
2016-2018
Postdoctoral Fellow
Yan-Jin Liu
Yan-Jin Liu
2019-2021
Postdoctoral Visiting Fellow