Brian J. Capaldo, Ph.D.

Brian J. Capaldo, Ph.D.

  • Center for Cancer Research
  • National Cancer Institute


Dr. Capaldo's research focuses on identifying best practices in bioinformatics and computational biology and applying these to biological problems to generate testable hypotheses in the field of prostate cancer. 

Areas of Expertise

1) bioinformatics 2) RNA sequencing 3) single cell 4) computational epigenomics 5) computational high parameter cytometry


Selected Key Publications

Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma

Capaldo BJ, Roller D, Axelrod MJ, Koeppel AF, Petricoin EF, Slingluff CL Jr, Weber MJ, Mackey AJ, Gioeli D, Bekiranov S.
PLoS One. 10(9): e0138210, 2015. [ Journal Article ]

An integrated framework using high-dimensional mass cytometry and fluorescent flow cytometry identifies discrete B cell subsets in patients with red meat allergy

Cox KM, Commins SP, Capaldo BJ, Workman LJ, Platts-Mills TAE, Amir ED, Lannigan JA, Schuyler AJ, Erickson LD.
Clin Exp Allergy. 49(5): 615-625, 2019. [ Journal Article ]