Rosandra N. Kaplan, M.D. Rosandra N. Kaplan, M.D., has been awarded tenure at NIH and appointed to Senior Investigator in the Pediatric Oncology Branch. Dr. Kaplan, a physician-scientist, developed the concept of the pre-metastatic niche, identifying microenvironmental changes occurring early in metastatic sites that regulate metastatic progression. She has recently developed new cell therapy approaches to reprogram these microenvironments to limit cancer progression. Nicholas D. Klemen, M.D. Nicholas D. Klemen, M.D., has joined the Surgery Branch as part of CCR’s Physician-Scientist Early Investigator Program. Dr. Klemen is a surgical oncologist who specializes in the treatment of gastrointestinal tumors, particularly those of the colon, pancreas and liver. Andra V. Krauze, M.D., F.R.C.P.C., D.A.B.R. Andra V. Krauze, M.D., F.R.C.P.C., D.A.B.R., has joined the Radiation Oncology Branch as part of CCR’s Physician-Scientist Early Investigator Program. Dr. Krauze is a radiation oncologist with a research interest in harnessing computational analyses of large-scale data to personalize management of patients with cancer and improve oncologic outcomes. Eros Lazzerini Denchi, Ph.D. Eros Lazzerini Denchi, Ph.D., has been awarded tenure at NIH and appointed to Senior Investigator in the Laboratory of Genome Integrity. Dr. Lazzerini Denchi’s research focuses on two fundamental aspects of telomere biology: the mechanism by which functional telomeres prevent DNA damage activation and the in vivo consequences of telomere dysfunction. Susan M. Lea, D.Phil., F.Med.Sci. Susan M. Lea, D.Phil., F.Med.Sci., has been appointed Chief of the Center for Structural Biology. Dr. Lea pioneered the use of mixed structural methods to study host-pathogen interactions and other medically important molecular pathways. Her laboratory uses and develops cutting-edge structural methods to define molecular mechanisms involved in health and disease states. 31
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