Rosalba  Salcedo, Ph.D.
Rosalba Salcedo, Ph.D.
Staff Scientist

Center for Cancer Research
National Cancer Institute

Bldg. 567, Room 207
Frederick, MD 21702-1201
301-846-6274

Dr. Salcedo's research focuses on the role of chronic inflammation in the promotion of cancer. She is using several genetic and chemical models of skin and colon carcinogenesis to elucidate the protective and detrimental effects of innate immune responses in the induction and subsequent outgrowth of tumors.

Areas of Expertise
1) chronic inflammation, 2) genetic and chemical models

Our research is focused on the role of chronic inflammation in the promotion of cancer. Several genetic and chemical models of skin and colon carcinogenesis are being used to elucidate the protective and detrimental effects of innate immune responses in the induction and subsequent outgrowth of tumors.

Selected Publications
  1. Iida N, Dzutsev A, Stewart CA, Smith L, Bouladoux N, Weingarten RA, Molina DA, Salcedo R, Back T, Cramer S, Dai RM, Kiu H, Cardone M, Naik S, Patri AK, Wang E, Marincola FM, Frank KM, Belkaid Y, Trinchieri G, Goldszmid RS.
    Science. 342: 967-70, 2013. [ Journal Article ]
  2. Golubeva Y, Salcedo R, Mueller C, Liotta LA, Espina V.
    Methods Mol Biol. 931: 213-57, 2013. [ Journal Article ]
  3. Salcedo R, Cataisson C, Hasan U, Yuspa SH, Trinchieri G.
    Trends Immunol. 34: 379-89, 2013. [ Journal Article ]
  4. Naik S, Bouladoux N, Wilhelm C, Molloy MJ, Salcedo R, Kastenmuller W, Deming C, Quinones M, Koo L, Conlan S, Spencer S, Hall JA, Dzutsev A, Kong H, Campbell DJ, Trinchieri G, Segre JA, Belkaid Y.
    Science. 337: 1115-9, 2012. [ Journal Article ]
  5. Stauffer JK, Orentas RJ, Lincoln E, Khan T, Salcedo R, Hixon JA, Back TC, Wei JS, Patidar R, Song Y, Hurd L, Tsokos M, Lai EW, Eisenhofer G, Weiss W, Khan J, Wigginton JM.
    Cancer Invest. 30: 343-63, 2012. [ Journal Article ]

Dr. Salcedo received her doctoral training in immunology at the Karolinska Institute at Stockholm, Sweden, graduating in 1996. In 1997, she joined the Laboratory of Molecular Immunoregulation under Dr. Joost J. Oppenheim and worked on projects regarding the roles of chemokines in angiogenesis and tumorigenesis. In 2002, she began working in the Pediatric Oncology Branch under Dr. Jon M. Wigginton, exploring novel approaches for the treatment of neuroblastoma by utilizing preclinical models. In October 2006, she joined the Cancer and Inflammation Program, under Dr. Giorgio Trinchieri.

Summary

Dr. Salcedo's research focuses on the role of chronic inflammation in the promotion of cancer. She is using several genetic and chemical models of skin and colon carcinogenesis to elucidate the protective and detrimental effects of innate immune responses in the induction and subsequent outgrowth of tumors.

Areas of Expertise
1) chronic inflammation, 2) genetic and chemical models

Research

Our research is focused on the role of chronic inflammation in the promotion of cancer. Several genetic and chemical models of skin and colon carcinogenesis are being used to elucidate the protective and detrimental effects of innate immune responses in the induction and subsequent outgrowth of tumors.

Publications

Selected Publications
  1. Iida N, Dzutsev A, Stewart CA, Smith L, Bouladoux N, Weingarten RA, Molina DA, Salcedo R, Back T, Cramer S, Dai RM, Kiu H, Cardone M, Naik S, Patri AK, Wang E, Marincola FM, Frank KM, Belkaid Y, Trinchieri G, Goldszmid RS.
    Science. 342: 967-70, 2013. [ Journal Article ]
  2. Golubeva Y, Salcedo R, Mueller C, Liotta LA, Espina V.
    Methods Mol Biol. 931: 213-57, 2013. [ Journal Article ]
  3. Salcedo R, Cataisson C, Hasan U, Yuspa SH, Trinchieri G.
    Trends Immunol. 34: 379-89, 2013. [ Journal Article ]
  4. Naik S, Bouladoux N, Wilhelm C, Molloy MJ, Salcedo R, Kastenmuller W, Deming C, Quinones M, Koo L, Conlan S, Spencer S, Hall JA, Dzutsev A, Kong H, Campbell DJ, Trinchieri G, Segre JA, Belkaid Y.
    Science. 337: 1115-9, 2012. [ Journal Article ]
  5. Stauffer JK, Orentas RJ, Lincoln E, Khan T, Salcedo R, Hixon JA, Back TC, Wei JS, Patidar R, Song Y, Hurd L, Tsokos M, Lai EW, Eisenhofer G, Weiss W, Khan J, Wigginton JM.
    Cancer Invest. 30: 343-63, 2012. [ Journal Article ]

Biography

Dr. Salcedo received her doctoral training in immunology at the Karolinska Institute at Stockholm, Sweden, graduating in 1996. In 1997, she joined the Laboratory of Molecular Immunoregulation under Dr. Joost J. Oppenheim and worked on projects regarding the roles of chemokines in angiogenesis and tumorigenesis. In 2002, she began working in the Pediatric Oncology Branch under Dr. Jon M. Wigginton, exploring novel approaches for the treatment of neuroblastoma by utilizing preclinical models. In October 2006, she joined the Cancer and Inflammation Program, under Dr. Giorgio Trinchieri.