Peritoneal mesothelioma with ALK-STRN fusion mapping breakpoint to exon 3 of STRN and intron 19 of ALK. The resulting fusion protein contains domains for the Striatin protein and the kinase domain for ALK.
Lab/Branch/Program:
Thoracic and GI Malignancies Branch
Citation:
I. Mian, Z. Abdullaev, B. Morrow, R. N. Kaplan, S. Gao, M. Miettinen, D. S. Schrump, V. Zgonc, J. S. Wei, J. Khan, S. Pack, R. Hassan, Anaplastic Lymphoma Kinase Gene Rearrangement in Children and Young Adults With Mesothelioma. J Thorac Oncol 15, 457-461 (2020).
Published Date:
November, 2019