CellMinerCDB for Integrative Cross-Database Genomics and Pharmacogenomics Analyses of Cancer Cell Lines

iScience cover, December 21, 2018

About the Cover:  Drugs and Genomic databases are directly accessible using the web-based CellMinerCDB resource (https://discover.nci.nih.gov/cellminercdb/). The drug in clinical trial LMP400 (indotecan) is represented together with a DNA molecule giving rise to genomic data, which are integrated to generate hypotheses on mechanisms of action and genomic signatures for precision medicine.

Lab/Branch/Program: 
Developmental Therapeutics Branch
Citation: 

CellMinerCDB for Integrative Cross-Database Genomics and Pharmacogenomics Analyses of Cancer Cell Lines. Rajapakse VN, Luna A, Yamade M,Loman L, Varma S, Sunshine M, Iorio F, Sousa FG, Elloumi F, Aladjem MI, Thomas A, Sander C, Kohn KW, Benes CH, Garnett M, Reinhold WC, Pommier Y. iScience Dec 21; 10: 247-264, 2018.

Published Date: 
December, 2018