A 4'-C-Ethynyl-2',3'-Dideoxynucleoside Analogue Highlights the Role of the 3'-OH in Anti-HIV Active 4'-C-Ethynyl-2'-deoxy Nucleosides

Cover of Journal of Medicinal Chemistry, October 7, 2004

Interaction of the β-L-enantiomer of a 4'-C-ethynyl-2',3'-dideoxynucleoside analogue (ent-14-TP) at the active site of HIV reverse transcriptase.

Lab/Branch/Program:

Chemical Biology Laboratory

Citation:

See: A 4'-C-Ethynyl-2',3'-Dideoxynucleoside Analogue Highlights the Role of the 3'-OH in Anti-HIV Active 4'-C-Ethynyl-2'-deoxy Nucleosides by Maqbool A. Siddiqui, Stephen H. Hughes, Paul L. Boyer, Hiroaki Mitsuya, Que N. Van, Clifford George, Stefan G. Sarafinanos, and Victor E. Marquez in the Journal of Medicinal Chemistry 2004, 47, 5041-5048.

Published Date:

October, 2004