Enhanced Stereoselectivity of a Cu(II) Complex Chiral Auxiliary in the Synthesis of Fmoc-L-γ-carboxyglutamic Acid

Cover of The Journal of Organic Chemistry, March 18, 2011

Bridging bioinorganic chemistry with asymmetric synthesis: a naturally occurring metalloprotein is used for the structure-based evolution of chiral auxiliaries that prove to be effective in the synthesis of Fmoc-L-γ-carboxyglutamic acid. 

 

Lab/Branch/Program: 
Chemical Biology Laboratory
Citation: 

See Enhanced Stereoselectivity of a Cu(II) Complex Chiral Auxiliary in the Synthesis of Fmoc-L-γ-carboxyglutamic Acid by Daniel Smith, Glenn Yap, James Kelley and Joel Schneider in the Journal of Organic Chemistry201176 (6), pp 1513–1520.

Published Date: 
March, 2011