Bridging bioinorganic chemistry with asymmetric synthesis: a naturally occurring metalloprotein is used for the structure-based evolution of chiral auxiliaries that prove to be effective in the synthesis of Fmoc-L-γ-carboxyglutamic acid.
Lab/Branch/Program:
Chemical Biology Laboratory
Citation:
See Enhanced Stereoselectivity of a Cu(II) Complex Chiral Auxiliary in the Synthesis of Fmoc-L-γ-carboxyglutamic Acid by Daniel Smith, Glenn Yap, James Kelley and Joel Schneider in the Journal of Organic Chemistry, 2011, 76 (6), pp 1513–1520.
Published Date:
March, 2011