October is Breast Cancer Awareness Month

breast cancer in a dish

Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. The cancer in these cells is driven by the ErbB2 gene.
Credit: NCI Center for Cancer Research, National Cancer Institute, National Institutes of Health (NCI Visuals Online)

To recognize Breast Cancer Awareness Month this October, we are highlighting our researchers who are making discoveries in this field. Dr. Gordon Hager reported last year that activated hormone receptors and other gene regulators help one another find new gene targets in breast cancer cells. Dr. Shyam Sharan develops mouse models to understand genetic variant in BRCA1 and BRCA2 genes. We also have a concentration of investigators studying breast cancer metastasis: Dr. Kent Hunter continues to pioneer the use of integrated genetic and genomic technologies to gain better understanding of the genes and cellular pathways that contribute to the metastatic process; Dr. Lalage Wakefield is examining the use of TGF-beta antagonists for the suppression of metastasis; and Dr. Patricia Steeg focuses on the molecular characterization of breast cancer progression. The Women’s Malignancies Branch conducts basic, translational and clinical research on cancers, such as breast cancer, that only or primarily affect females. Explore our website to find the currently open and enrolling clinical trials on breast cancer. To learn about other CCR researchers who are conducting breast cancer-related research, search our website.

Summary Posted: 10/2017