Lung Cancer Research

Lung cancer cells

Lung cancer cells
Image credit: NCI Visuals Online

Our research portfolio in lung cancer is quite diverse and includes basic and clinical researchers pursuing various approaches to study lung cancer. Our basic research projects examine pathways driving lung tumorigenesis, the preclinical development of therapeutics in lung cancer models and the work of our Comparative Oncology Program that includes the study of pet dogs with lung cancer.

Some of our groups use integrative and translational approaches to study the genetics and biology behind health disparities in lung cancer and the effects of environmental exposures linked to lung cancer. Our Thoracic and GI Malignancies Branch (TGMB) and Thoracic Surgery Branch both integrate and synergize multidisciplinary clinical and basic research pertaining to cancers of the lungs and airways, chest cavity (thorax).

Anish Thomas is a clinical researcher with a focus on small cell lung cancer (SCLC), one of the most aggressive human cancers. Brid Ryan's lab oversees an integrative and translational approach to lung cancer research, examining the genetic, environmental, and biological contributions to racial disparities in lung cancer incidence. Azam Ghafoor is a research physician whose clinical and translational research focuses on investigating the clinical use of immunotoxin therapy and immunotherapy in thoracic malignancies such as mesothelioma and non-small cell lung cancers. Haobin Chen's research focuses on developing novel epigenetic therapies for small cell lung cancer. Nitin Roper is a physician scientist with a research focus on high-grade neuroendocrine tumors, including small cell lung cancers, bladder, prostate, pancreatic and non-small cell cancers that transform to high-grade neuroendocrine cancers.

We have several clinical trials that are testing therapies such as immunotherapy for lung cancer patients as well as teams launching precision medicine studies of lung cancer. Click here for a full list of our lung cancer trials.

Summary Posted: Fri, 11/01/2019