New clinical trial studies immunotherapy for several types of lymphoma


Lymphoma is a cancer of the lymphatic system, the body’s disease-fighting network. Several types of lymphoma such as Hodgkin lymphoma and T-cell lymphoma carry a protein on their membranes called CD30. James N. Kochenderfer, M.D., of the Experimental Transplantation and Immunology Branch is studying a new technique for treating lymphomas that express CD30. T cells, a type of immune cell, are collected from the patient’s own blood. The cells are then engineered to produce special receptors on their surface called chimeric antigen receptors (CARs). CARs are proteins that allow the T cells to recognize a specific protein on tumor cells. These T cells, which can now recognize and kill specific cancer cells, are then reintroduced into the patient. For more information on this trial, visit: https://clinicaltrials.gov/ct2/show/NCT03049449.

Summary Posted: 03/2017