Clinical trial for patients with relapsed/refractory B-cell malignancies now recruiting
B-cell lymphomas are blood cancers that affect B-cells, white blood cells that develop and mature in bone marrow in the core of most bones. Mark Roschewski, M.D., of the Lymphoid Malignancies Branch is leading a study of a new treatment for B-cell lymphomas that have not responded to radiation and chemotherapy.
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B-cell lymphomas are blood cancers that affect B-cells, white blood cells that develop and mature in bone marrow in the core of most bones. B-cells are part of the immune system that protects the body against infectious disease and foreign invaders. Mark Roschewski, M.D, of the Lymphoid Malignancies Branch is leading a study of a new treatment for B-cell lymphomas that have not responded to radiation and chemotherapy. Investigators hope that combining acalabrutinib and vistusertib will slow the growth of malignant B-cells, as these drugs interfere with different types of kinases – enzymes that play a vital role in regulating B-cell growth and activity. Both drugs have anticancer activity and studies suggest they may be even more effective when used together.
For more information about this trial, please visit: https://ccr.cancer.gov/Lymphoid-Malignancies-Branch/mark-j-roschewski.
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Summary Posted: 11/2017