Luowei  Li, Ph.D.
Luowei Li, Ph.D.
Staff Scientist

Center for Cancer Research
National Cancer Institute

Building 37, Room 4060
Bethesda, MD 20892
301-496-2383

Dr. Li has focused her research on understanding the role of several major signal transduction pathways on epidermal proliferation, differentiation, and transformation. She is also interested in exploring the interaction between tumor cells and their microenvironment. Recently, she has been evaluating pathway specific agents for cancer therapy.

Areas of Expertise
cancer therapy

Dr. Li has focused her research on understanding the role of several major signal transduction pathways on epidermal proliferation, differentiation, and transformation. She is also interested in exploring the interaction between tumor cells and their microenvironment. Recently, she has been evaluating pathway specific agents for cancer therapy.

Selected Publications
  1. Yang D, Kedei N, Li L, Tao J, Velasquez JF, Michalowski AM, Tóth BI, Marincsák R, Varga A, Bíró T, Yuspa SH, Blumberg PM.
    Cancer Res.. 70: 7905-17, 2010. [ Journal Article ]
  2. Li L, Shukla S, Lee A, Garfield SH, Maloney DJ, Ambudkar SV, Yuspa SH.
    Cancer Res.. 70: 4509-19, 2010. [ Journal Article ]
  3. Park JE, Li L, Park J, Knecht R, Strebhardt K, Yuspa SH, Lee KS.
    Proc. Natl. Acad. Sci. U.S.A.. 106: 1725-30, 2009. [ Journal Article ]
  4. Suh KS, Mutoh M, Mutoh T, Li L, Ryscavage A, Crutchley JM, Dumont RA, Cheng C, Yuspa SH.
    J. Cell. Sci.. 120: 2631-40, 2007. [ Journal Article ]
  5. Stepp MA, Liu Y, Pal-Ghosh S, Jurjus RA, Tadvalkar G, Sekaran A, Losicco K, Jiang L, Larsen M, Li L, Yuspa SH.
    J. Cell. Sci.. 120: 2851-63, 2007. [ Journal Article ]

Dr. Li received her Bachelor Degree in Biophysics from Fudan University in Shanghai, China. She was an instructor for Department of Biotechnology in Tsinghua University, Beijing, China before enrolled in a joint graduate program between W. Alton Jones Science Center in Lake Placid, NY and Tsinghua University. In 1993, she received her PhD in Biochemistry from a joint program between Clarkson University, Potsdam, New York, and the W. Alton Jones Cell Science Center. Her PhD research was focused on the contribution of calcium homeostasis to the terminal differentiation of keratinocytes. She was a postdoctoral fellow in the Laboratory of Cellular Carcinogenesis and Tumor Promotion in National Cancer Institute and later promoted to Staff Scientist under the direction of Dr. Stuart H. Yuspa.

Summary

Dr. Li has focused her research on understanding the role of several major signal transduction pathways on epidermal proliferation, differentiation, and transformation. She is also interested in exploring the interaction between tumor cells and their microenvironment. Recently, she has been evaluating pathway specific agents for cancer therapy.

Areas of Expertise
cancer therapy

Research

Dr. Li has focused her research on understanding the role of several major signal transduction pathways on epidermal proliferation, differentiation, and transformation. She is also interested in exploring the interaction between tumor cells and their microenvironment. Recently, she has been evaluating pathway specific agents for cancer therapy.

Publications

Selected Publications
  1. Yang D, Kedei N, Li L, Tao J, Velasquez JF, Michalowski AM, Tóth BI, Marincsák R, Varga A, Bíró T, Yuspa SH, Blumberg PM.
    Cancer Res.. 70: 7905-17, 2010. [ Journal Article ]
  2. Li L, Shukla S, Lee A, Garfield SH, Maloney DJ, Ambudkar SV, Yuspa SH.
    Cancer Res.. 70: 4509-19, 2010. [ Journal Article ]
  3. Park JE, Li L, Park J, Knecht R, Strebhardt K, Yuspa SH, Lee KS.
    Proc. Natl. Acad. Sci. U.S.A.. 106: 1725-30, 2009. [ Journal Article ]
  4. Suh KS, Mutoh M, Mutoh T, Li L, Ryscavage A, Crutchley JM, Dumont RA, Cheng C, Yuspa SH.
    J. Cell. Sci.. 120: 2631-40, 2007. [ Journal Article ]
  5. Stepp MA, Liu Y, Pal-Ghosh S, Jurjus RA, Tadvalkar G, Sekaran A, Losicco K, Jiang L, Larsen M, Li L, Yuspa SH.
    J. Cell. Sci.. 120: 2851-63, 2007. [ Journal Article ]

Biography

Dr. Li received her Bachelor Degree in Biophysics from Fudan University in Shanghai, China. She was an instructor for Department of Biotechnology in Tsinghua University, Beijing, China before enrolled in a joint graduate program between W. Alton Jones Science Center in Lake Placid, NY and Tsinghua University. In 1993, she received her PhD in Biochemistry from a joint program between Clarkson University, Potsdam, New York, and the W. Alton Jones Cell Science Center. Her PhD research was focused on the contribution of calcium homeostasis to the terminal differentiation of keratinocytes. She was a postdoctoral fellow in the Laboratory of Cellular Carcinogenesis and Tumor Promotion in National Cancer Institute and later promoted to Staff Scientist under the direction of Dr. Stuart H. Yuspa.