Antoun Toubaji, M.D.

Antoun Toubaji, M.D.
Associate Research Physician

Dr. Toubaji is a genitourinary (GU) pathologist. He  is interested in studying GU solid tumors, particularly prostate cancer. His research focuses on prostate cancer significant molecular alterations, diagnostic and prognostic biomarkers, and validation of artificial intelligence (AI) and deep learning algorithms for detection and grading of prostate cancer. 

Areas of Expertise

1) prostate cancer, 2) molecular genetics and biomarkers, 3) genitourinary malignancies

Contact Info

Antoun Toubaji, M.D.
Center for Cancer Research
National Cancer Institute
Building 10, Room 2S235G
Bethesda, MD 20814
Ph: 240-858-7186
antoun.toubaji@nih.gov

I am an academic genitourinary (GU) pathologist and I am passionate about studying the histological features of GU malignancies. However, I am very interested in studying the genetic alteration of these tumors, as I believe it is the path for the future in diagnostic pathology. As prostate cancer remains a major health problem in the world, discovery and addition of new biomarkers and genetic alterations enhances the accuracy of prostate cancer clinicopathologic parameters (PSA, Gleason grade, stage) for the decision-making process toward optimal patient clinical management. Furthermore, application of artificial intelligence (AI) and deep learning systems enhances our accuracy and consistency in detecting, targeting and evaluating prostate cancer.

NIH Scientific Focus Areas:
Cancer Biology, Clinical Research, Computational Biology, Genetics and Genomics, Molecular Biology and Biochemistry
View Dr. Toubaji's PubMed Summary.

Selected Key Publications

  1. Toubaji A, Albadine R, Meeker AK, Isaacs WB, Lotan T, Haffner MC, Chaux A, Epstein JI, Han M, Walsh PC, Partin AW, De Marzo AM, Platz EA, Netto GJ.
    Mod Pathol. 24(11): 1511-20, 2011. [ Journal Article ]
  2. Haffner MC, Aryee MJ, Toubaji A, Esopi DM, Albadine R, Gurel B, Isaacs WB, Bova GS, Liu W, Xu J, Meeker AK, Netto G, De Marzo AM, Nelson WG, Yegnasubramanian S.
    Nat Genet. 42(8): 668-75, 2010. [ Journal Article ]
  3. Chen YB, Brannon AR, Toubaji A, Dudas ME, Won HH, Al-Ahmadie HA, Fine SW, Gopalan A, Frizzell N, Voss MH, Russo P, Berger MF, Tickoo SK, Reuter VE.
    Am J Surg Pathol. 38(5): 627-37, 2014. [ Journal Article ]
  4. Toubaji A, Sutcliffe S, Chaux A, Lecksell K, Hicks J, De Marzo AM, Platz EA, Netto GJ.
    Hum Pathol. 43(11): 1852-65, 2012. [ Journal Article ]
  5. Wu RC, Young IC, Chen YF, Chuang ST, Toubaji A, Wu MY.
    Nat Commun. 10(1): 4332, 2019. [ Journal Article ]

Dr. Toubaji received his medical degree from Damascus University Faculty of Medicine and has completed cancer research fellowships at the National Cancer Institute and at the Johns Hopkins Medical Institutions/Department of Pathology. He has completed a pathology residency training (AP/CP) at Georgetown University, an oncologic surgical pathology fellowship and a genitourinary pathology fellowship at Memorial Sloan Kettering Cancer Center. Previously, Dr. Toubaji has held positions as an assistant professor/staff pathologist at the George Washington University Department of Pathology.