Past Seminars

2022 Past Seminars

Wed 16-November
Evaluation of biomarkers related to B7H3-PBD-ADC response in mCRPC organoid models
Speaker: Supreet Agarwal, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 12-October
High-throughput organoid screening reveals a docetaxel-resistant phenotype of prostate cancer
Speaker: Ilya Senatorov, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 28-September
Functional Interrogation of HOXB13 Using CRISPR-Cas9 Base Editors
Speaker: Sasha Adamovich, Takeda Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 14-September
Investigating the Regulation of FOLH1 using CRISPRi Methods
Speaker: Maggie White, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 27-July
High resolution dissection of the AR enhancer using Cas9 base editors
Speaker: Shin-Ai Lee, Takeda Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 20-July
What does FDG PET tell us about prostate cancer?
Speaker: Peter Choyke, Chief, Molecular Imaging Branch, NCI, NIH, Bethesda, MD

Wed 13-July
Dissecting tumor and tumor microenvironment with spatial transcriptomics
Speaker: Anson Ku, Sowalsky Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 27-April
Identification of RB1/TP53 loss dependent transcription and epigenetic factors encoding lineage plasticity and growth in prostate cancer models
Speaker: Sonam Raj, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 9-March
Investigating the mechanisms of tumor cell response and resistance to androgen deprivation therapy
Speaker: Scott Wilkinson, Sowalsky Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

2021 Past Seminars

Wed 17-November
B7-H3 is a potential therapeutic target in advanced metastatic prostate cancer
Speaker: Supreet Agarwal, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 3-November
High resolution mapping of AR enhancer using extended PAM base editor screens
Speaker: Shin-Ai Lee, Takeda Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 6-October
Understanding the role of PTEN in DNA Damage Repair in Hormone-Driven Cancers
Speaker: Emily Kolyvas, Kellyy Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 22-September
Investigating AR’s Regulation of FOLH1 using CRISPR-Cas9 Methods
Speaker: Maggie White, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 18-August
In Silico Analysis of LNCaP ChIP-seq Data to Identify Putative MYC Targets
Speaker: Nichelle Whitlock, Sowalsky Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 11-August
Using Type I CRISPR to examine prostate cancer regulatory elements
Speaker: Sasha Adamovich, Takeda Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 14-July
Transciptomic landscape of de novo iADT resistant tumors 
Speaker: Anson Ku, Sowalsky Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 12-May
Epigenomic landscape of advanced bladder cancer from patient autopsy samples
Speaker: Andre Kidd, Takeda Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 14-April
Identification and characterization of subpopulations in patient-derived organoid models of prostate cancer
Speaker: Mike Beshiri, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 24-March
High throughput organoid drug screening reveals drug sensitivity and resistance profiles for phenotypically distinct models of prostate cancer
Speaker: Ilya Senatorov, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 17-March
Genomic Instability: causes, consequences and opportunities
Speaker: Travis Stracker, Investigator, Radiation Oncology Branch, NCI, NIH, Bethesda, MD

Wed 24-February
Using CRISPR technologies to uncover the functional and regulatory complexity of the mammalian transcriptome
Speaker: Thomas Gonatopoulos-Pournatzis,Stadtman Investigator, RNA Biology Laboratory, NCI, NIH, Bethesda, MD

Wed 27-January
Leveraging mouse microenvironment transcriptomic profiles for identifying interactions with PDX-derived bone metastases
Speaker: Brian Capaldo, Staff Scientist, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 13-January
Developing prostate cancer metastasis models with LuCaP PDXs to understand the mechanism and identify effective treatment of mCRPC
Speaker: Ivy Yin, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

2020 Past Seminars

Wed 14-October
Characterizing prostate cancer organoids with prostate specific membrane Antigen (PSMA)-targeted and metabolic PET imaging agent
Speaker: Maggie White, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 30-September
MYC overexpression, tumor suppressor loss, and inflammation: modeling prostate carcinogenesis in rodents
Speaker: Charles Bieberich, Professor, Department of Biological Sciences, University of Maryland Baltimore County, Catonsville, MD

Wed 16-September
Identification and characterization of phenotypically-distinct subpopulations in patient-derived organoid models of prostate cancer lineage plasticity
Speaker: Mike Beshiri, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 26-August
An investigation of how inflammation may underlie the excessive burden of prostate cancer in men of African ancestry
Speaker: Stefan Ambs, Senior Investigator, Laboratory of Human Carcinogenesis, NCI, NIH, Bethesda, MD

Wed 12-August
Role of Interferon signaling in advanced prostate cancer
Speaker: Supreet Agarwal, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 29-July
Role of BAP1 and INO80 in genome stability and tumorigenesis
Speaker: Shin-Ai Lee, Takeda Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 15-July
Genetic contribution of MYC to development of primary prostate cancer
Speaker: Nichelle Whitlock, Sowalsky Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 10-June
Tumor evolution and diversity in locally-aggressive prostate cancer
Speaker: Scott Wilkinson, Sowalsky Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 3-June
Neuroendocrine signatures in Small Cell Lung Cancers and Beyond
Speaker: Yves Pommier,  Chief, Developmental Therapeutics Branch, NCI, NIH, Bethesda, MD

Wed 13-May
Finding genes essential for cell viability and therapeutic targets in prostate cancer models using CRISPR Dropout screen
Speaker: Sonam Raj, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 29-April
Alterations in AR regulome following response to kinase inhibitors
Speaker: Remi Adelaiye-Ogala, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 15-April
Molecular phenotyping of neuroendocrine prostate cancer
Speaker: Brian Capaldo, Staff Scientist, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 5-February
Prostate cancer compound sensitivity profiling via PDX-organoid high-throughput drug screen
Speaker: Ilya Senatorov, Kelly Lab, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD

Wed 22-January
Targeting the transcription factors that determine cancer cell identity
Speaker: Berkley Gryder, Earl Stadtman Seminar, Genetics Branch, NCI, NIH, Bethesda, MD

Wed 8-January
Identifying and interrogating epigenetic drivers of prostate cancer tumorigenesis
Speaker: David Takeda, Lasker Clinical Research Scholar, Laboratory of Genitourinary Cancer Pathogenesis, NCI, NIH, Bethesda, MD