Jung-Eun Park, Ph.D.
Jung-Eun  Park, Ph.D.
Staff Scientist

Dr. Park's primary research interest lies in understanding the physiological functions of two functionally distinct mammalian polo-like kinases, Plk1 and Plk4, which appear to play key roles in mitotic progression and centriole duplication, respectively. Dr. Park is also interested in developing anti-Plk1 therapeutic agents by exploiting both potential leads from our own research and from the unique resources that NCI provides to the intramural community.

Areas of Expertise
kinases

Contact Info

Jung-Eun Park, Ph.D.
Center for Cancer Research
National Cancer Institute
Building 37, Room 3118
Bethesda, MD 20892-4254
301-435-8894
parkju@mail.nih.gov

Dr. Park's primary research interest lies in understanding the physiological functions of two functionally distinct mammalian polo-like kinases, Plk1 and Plk4, which appear to play key roles in mitotic progression and centriole duplication, respectively. Dr. Park is also interested in developing anti-Plk1 therapeutic agents by exploiting both potential leads from our own research and from the unique resources that NCI provides to the intramural community.

Selected Publications
  1. Kim TS, Park JE, Shukla A, Choi S, Murugan RN, Lee JH, Ahn M, Rhee K, Bang JK, Kim BY, Loncarek J, Erikson RL, Lee KS.
    Proc. Natl. Acad. Sci. U.S.A.. 110: E4849-57, 2013. [ Journal Article ]
  2. Park JE, Erikson RL, Lee KS.
    Proc. Natl. Acad. Sci. U.S.A.. 108: 8200-5, 2011. [ Journal Article ]
  3. Liu F, Park J, Qian W, Lim D, Graber M, Berg T, Yaffe MB, Lee KS, Burke TR.
    Nat. Chem. Biol.. 7: 595-601, 2011. [ Journal Article ]
  4. Park JE, Li L, Park J, Knecht R, Strebhardt K, Yuspa SH, Lee KS.
    Proc. Natl. Acad. Sci. U.S.A.. 106: 1725-30, 2009. [ Journal Article ]
  5. Yun S, Moulaei T, Lim D, Bang JK, Park J, Shenoy SR, Liu F, Kang YH, Liao C, Soung N, Lee S, Yoon D, Lim Y, Lee D, Otaka A, Appella E, McMahon JB, Nicklaus MC, Burke TR, Yaffe MB, Wlodawer A, Lee KS.
    Nat. Struct. Mol. Biol.. 16: 876-82, 2009. [ Journal Article ]

Dr. Jung-Eun Park joined the NIH in 2002 as an Office of International Affairs' predoctoral fellow and received her Ph.D. in 2004 from the Department of Biology at the Dong-A University, South Korea. She then obtained her postdoctoral research training at the NCI and became a staff scientist in the Laboratory of Metabolism, CCR, in 2010.

Research

Dr. Park's primary research interest lies in understanding the physiological functions of two functionally distinct mammalian polo-like kinases, Plk1 and Plk4, which appear to play key roles in mitotic progression and centriole duplication, respectively. Dr. Park is also interested in developing anti-Plk1 therapeutic agents by exploiting both potential leads from our own research and from the unique resources that NCI provides to the intramural community.

Publications

Selected Publications
  1. Kim TS, Park JE, Shukla A, Choi S, Murugan RN, Lee JH, Ahn M, Rhee K, Bang JK, Kim BY, Loncarek J, Erikson RL, Lee KS.
    Proc. Natl. Acad. Sci. U.S.A.. 110: E4849-57, 2013. [ Journal Article ]
  2. Park JE, Erikson RL, Lee KS.
    Proc. Natl. Acad. Sci. U.S.A.. 108: 8200-5, 2011. [ Journal Article ]
  3. Liu F, Park J, Qian W, Lim D, Graber M, Berg T, Yaffe MB, Lee KS, Burke TR.
    Nat. Chem. Biol.. 7: 595-601, 2011. [ Journal Article ]
  4. Park JE, Li L, Park J, Knecht R, Strebhardt K, Yuspa SH, Lee KS.
    Proc. Natl. Acad. Sci. U.S.A.. 106: 1725-30, 2009. [ Journal Article ]
  5. Yun S, Moulaei T, Lim D, Bang JK, Park J, Shenoy SR, Liu F, Kang YH, Liao C, Soung N, Lee S, Yoon D, Lim Y, Lee D, Otaka A, Appella E, McMahon JB, Nicklaus MC, Burke TR, Yaffe MB, Wlodawer A, Lee KS.
    Nat. Struct. Mol. Biol.. 16: 876-82, 2009. [ Journal Article ]

Biography

Dr. Jung-Eun Park joined the NIH in 2002 as an Office of International Affairs' predoctoral fellow and received her Ph.D. in 2004 from the Department of Biology at the Dong-A University, South Korea. She then obtained her postdoctoral research training at the NCI and became a staff scientist in the Laboratory of Metabolism, CCR, in 2010.