Frances T. Hakim, Ph.D.
Frances T. Hakim, Ph.D.
Staff Scientist
Head, Preclinical Support Services

Center for Cancer Research
National Cancer Institute

Building 10, Room 12C216
Bethesda, MD 20892-1203
301-402-3627

Fran Hakim has spent most of her research career at NIH. She completed her doctoral research analyzing a murine inflammatory arthritis model under Joost Oppenheim and her postdoctoral work on murine GVHD models under Gene Shearer. Joining the laboratory of Ron Gress, she focused on immune reconstitution of T and NK cells in the clinical transplant setting. Since 2005 she has headed a transplantation immunology research core facility supporting the clinical protocols of Experimental Transplantation and Immunology Branch, including novel trials on IL-7 therapy, T cell immunotherapy, and autologous transplantation for systemic lupus. Her primary research interests focus on immune reconstitution and chronic graft versus host disease.

Areas of Expertise
preclinical support

Preclinical Support Service

Selected Publications
  1. Kochenderfer JN, Dudley ME, Carpenter RO, Kassim SH, Rose JJ, Telford WG, Hakim FT, Halverson DC, Fowler DH, Hardy NM, Mato AR, Hickstein DD, Gea-Banacloche JC, Pavletic SZ, Sportes C, Maric I, Feldman SA, Hansen BG, Wilder JS, Blacklock-Schuver B, Jena B, Bishop MR, Gress RE, Rosenberg SA.
    Blood. 122: 4129-39, 2013. [ Journal Article ]
  2. Salit RB, Fowler DH, Dean RM, Pavletic SZ, Hakim FT, Steinberg SM, Hardy NT, Sportes C, Gress RE, Bishop MR.
    Biol. Blood Marrow Transplant.. 19: 1509-13, 2013. [ Journal Article ]
  3. Lee-Chang C, Bodogai M, Moritoh K, Olkhanud PB, Chan AC, Croft M, Mattison JA, Holst PJ, Gress RE, Ferrucci L, Hakim F, Biragyn A.
    Blood. [Epub ahead of print], 2014. [ Journal Article ]
  4. Imanguli MM, Cowen EW, Rose J, Dhamala S, Swaim W, Lafond S, Yagi B, Gress RE, Pavletic SZ, Hakim FT.
    Leukemia. [Epub ahead of print], 2014. [ Journal Article ]
  5. Carpenter RO, Evbuomwan MO, Pittaluga S, Rose JJ, Raffeld M, Yang S, Gress RE, Hakim FT, Kochenderfer JN.
    Clin. Cancer Res.. 19: 2048-60, 2013. [ Journal Article ]

Fran Hakim has spent most of her research career at NIH. She completed her doctoral research analyzing a murine inflammatory arthritis model under Joost Oppenheim and her postdoctoral work on murine GVHD models under Gene Shearer. Joining the laboratory of Ron Gress, she focused on immune reconstitution of T and NK cells in the clinical transplant setting. Since 2005 she has headed a transplantation immunology research core facility supporting the clinical protocols of Experimental Transplantation and Immunology Branch, including novel trials on IL-7 therapy, T cell immunotherapy, and autologous transplantation for systemic lupus. Her primary research interests focus on immune reconstitution and chronic graft versus host disease.

Name Position
Monica Cho Postbaccalaureate Fellow
Susan Dhamala Postbaccalaureate Fellow
Vicki S. Fellowes Research Biologist
Jacqueline Ford Summer Student
Matin Imanguli D.D.S Special Volunteer
Jeremy J. Rose Research Biologist
Xiao-Yi Yan M.D. Research Biologist

Summary

Fran Hakim has spent most of her research career at NIH. She completed her doctoral research analyzing a murine inflammatory arthritis model under Joost Oppenheim and her postdoctoral work on murine GVHD models under Gene Shearer. Joining the laboratory of Ron Gress, she focused on immune reconstitution of T and NK cells in the clinical transplant setting. Since 2005 she has headed a transplantation immunology research core facility supporting the clinical protocols of Experimental Transplantation and Immunology Branch, including novel trials on IL-7 therapy, T cell immunotherapy, and autologous transplantation for systemic lupus. Her primary research interests focus on immune reconstitution and chronic graft versus host disease.

Areas of Expertise
preclinical support

Research

Preclinical Support Service

Publications

Selected Publications
  1. Kochenderfer JN, Dudley ME, Carpenter RO, Kassim SH, Rose JJ, Telford WG, Hakim FT, Halverson DC, Fowler DH, Hardy NM, Mato AR, Hickstein DD, Gea-Banacloche JC, Pavletic SZ, Sportes C, Maric I, Feldman SA, Hansen BG, Wilder JS, Blacklock-Schuver B, Jena B, Bishop MR, Gress RE, Rosenberg SA.
    Blood. 122: 4129-39, 2013. [ Journal Article ]
  2. Salit RB, Fowler DH, Dean RM, Pavletic SZ, Hakim FT, Steinberg SM, Hardy NT, Sportes C, Gress RE, Bishop MR.
    Biol. Blood Marrow Transplant.. 19: 1509-13, 2013. [ Journal Article ]
  3. Lee-Chang C, Bodogai M, Moritoh K, Olkhanud PB, Chan AC, Croft M, Mattison JA, Holst PJ, Gress RE, Ferrucci L, Hakim F, Biragyn A.
    Blood. [Epub ahead of print], 2014. [ Journal Article ]
  4. Imanguli MM, Cowen EW, Rose J, Dhamala S, Swaim W, Lafond S, Yagi B, Gress RE, Pavletic SZ, Hakim FT.
    Leukemia. [Epub ahead of print], 2014. [ Journal Article ]
  5. Carpenter RO, Evbuomwan MO, Pittaluga S, Rose JJ, Raffeld M, Yang S, Gress RE, Hakim FT, Kochenderfer JN.
    Clin. Cancer Res.. 19: 2048-60, 2013. [ Journal Article ]

Biography

Fran Hakim has spent most of her research career at NIH. She completed her doctoral research analyzing a murine inflammatory arthritis model under Joost Oppenheim and her postdoctoral work on murine GVHD models under Gene Shearer. Joining the laboratory of Ron Gress, she focused on immune reconstitution of T and NK cells in the clinical transplant setting. Since 2005 she has headed a transplantation immunology research core facility supporting the clinical protocols of Experimental Transplantation and Immunology Branch, including novel trials on IL-7 therapy, T cell immunotherapy, and autologous transplantation for systemic lupus. Her primary research interests focus on immune reconstitution and chronic graft versus host disease.

Team

Name Position
Monica Cho Postbaccalaureate Fellow
Susan Dhamala Postbaccalaureate Fellow
Vicki S. Fellowes Research Biologist
Jacqueline Ford Summer Student
Matin Imanguli D.D.S Special Volunteer
Jeremy J. Rose Research Biologist
Xiao-Yi Yan M.D. Research Biologist