The Experimental Transplantation and Immunotherapy Branch is dedicated to coordinated efforts in basic, preclinical and clinical investigations in the areas of immunotherapy, immune reconstitution, T cell biology, hematopoiesis, and hematopoietic stem cell transplantation. The goal is to generate information from basic and preclinical investigations to develop new, curative hematopoietic stem cell transplant-based therapies for cancer. Information from new treatment protocols (including novel endpoints generated in the course of basic/preclinical research) is used to generate new questions and studies in the basic and preclinical research efforts. The branch emphasizes excellence in these endeavors and acts to maximize strengths present in the community at large by vigorous intramural and extramural interactions and collaborations.
-
Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Experimental Transplantation and Immunotherapy Branch Studies
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0051Investigator Christian S. Hinrichs, M.D. -
A Phase 1/1b Study of Enhancement of Immune Reconstitution and Vaccine Responses with Administration of Recombinant Human IL-7-hyFc (NT-I7) in Older Subjects Following Chemotherapy
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0134Investigator Ronald E. Gress, M.D. -
A Phase II study of Neoadjuvant E7 TCR T Cell Immunotherapy for Borderline Resectable and Unresectable Stage I HPV-Associated Oropharyngeal Cancer
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0130Investigator Christian S. Hinrichs, M.D. -
Phase I/II Study De-intensifying Exposure of Post-transplantation Cyclophosphamide as GVHD Prophylaxis after HLA-haploidentical Hematopoietic Cell Transplantation for Hematologic Malignancies
Open - RecruitingNCI Protocol ID NCI-19-C-0112Investigator Christopher G. Kanakry, M.D. -
A Phase II Study of Immunotherapy with E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions
Open - RecruitingNCI Protocol ID NCI-19-C-0091Investigator Christian S. Hinrichs, M.D. -
Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Peripheral T cell Lymphoma
Open - RecruitingNCI Protocol ID NCI-19-C-0085Investigator Jennifer A. Kanakry, M.D. -
Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation
Open - RecruitingNCI Protocol ID NCI-18-C-0135Investigator Jennifer A. Kanakry, M.D. -
A Phase I/II Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 for HPV-Associated Cancers
Open - RecruitingNCI Protocol ID NCI-16-C-0154Investigator Christian S. Hinrichs, M.D. -
Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy Subjects for the Expansion of T Cells for Adoptive Cell Therapy
Open - RecruitingNCI Protocol ID NCI-16-C-0138Investigator Christian S. Hinrichs, M.D. -
Biospecimen Procurement for Experimental Transplantation and Immunology Branch Immunotherapy Protocols
Open - RecruitingNCI Protocol ID NCI-16-C-0061Investigator Christian S. Hinrichs, M.D. -
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
Open - RecruitingNCI Protocol ID NCI-16-C-0003Investigator Jennifer A. Kanakry, M.D. -
Autologous and Related Allogeneic Hematopoietic Stem Cell Transplant and Cellular Therapies Data Submission to the Center for International Blood and Marrow Transplant Research (CIBMTR) and the National Marrow Donor Program (NMDP)
Open - RecruitingNCI Protocol ID NCI-09-C-0053Investigator Ronald E. Gress, M.D.
| Position | Keywords | Contact Name | Contact E-mail | Number of Positions |
|---|---|---|---|---|
| Postdoctoral Fellow- Cell Therapy/Hematopoietic Cell Transplantation |
immunology, immunotherapy, transplantation |
Christopher Kanakry | 1 |
ETIB Clinical Core
Personnel in this Core provide the infrastructural expertise for excellence in patient care and clinical research.
Judy L. Baruffaldi, Patient Care Coordinator (Contr.)
Tracey Chinn, RN, BSN, MPM, Head, Clinical Studies Unit
Sarfraz A. Memon, M.D., Research Chemist
Scott Napier, Physician Assistant
Eun Soo Paek, RN, BSN, Clinical Apheresis Nurse
Laura Skeffington, B.S., Physician Assistant (Contr.)
Anita Stokes, Nurse Practitioner
Jennifer Wilders, RN, Nurse Specialist (Contr.)
About
The Experimental Transplantation and Immunotherapy Branch is dedicated to coordinated efforts in basic, preclinical and clinical investigations in the areas of immunotherapy, immune reconstitution, T cell biology, hematopoiesis, and hematopoietic stem cell transplantation. The goal is to generate information from basic and preclinical investigations to develop new, curative hematopoietic stem cell transplant-based therapies for cancer. Information from new treatment protocols (including novel endpoints generated in the course of basic/preclinical research) is used to generate new questions and studies in the basic and preclinical research efforts. The branch emphasizes excellence in these endeavors and acts to maximize strengths present in the community at large by vigorous intramural and extramural interactions and collaborations.
Clinical Trials
-
Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Experimental Transplantation and Immunotherapy Branch Studies
Open - Not yet RecruitingNCI Protocol ID NCI-20-C-0051Investigator Christian S. Hinrichs, M.D. -
A Phase 1/1b Study of Enhancement of Immune Reconstitution and Vaccine Responses with Administration of Recombinant Human IL-7-hyFc (NT-I7) in Older Subjects Following Chemotherapy
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0134Investigator Ronald E. Gress, M.D. -
A Phase II study of Neoadjuvant E7 TCR T Cell Immunotherapy for Borderline Resectable and Unresectable Stage I HPV-Associated Oropharyngeal Cancer
Open - Not yet RecruitingNCI Protocol ID NCI-19-C-0130Investigator Christian S. Hinrichs, M.D. -
Phase I/II Study De-intensifying Exposure of Post-transplantation Cyclophosphamide as GVHD Prophylaxis after HLA-haploidentical Hematopoietic Cell Transplantation for Hematologic Malignancies
Open - RecruitingNCI Protocol ID NCI-19-C-0112Investigator Christopher G. Kanakry, M.D. -
A Phase II Study of Immunotherapy with E7 T Cell Receptor T Cells for Vulvar High-Grade Squamous Intraepithelial Lesions
Open - RecruitingNCI Protocol ID NCI-19-C-0091Investigator Christian S. Hinrichs, M.D. -
Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Peripheral T cell Lymphoma
Open - RecruitingNCI Protocol ID NCI-19-C-0085Investigator Jennifer A. Kanakry, M.D. -
Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation
Open - RecruitingNCI Protocol ID NCI-18-C-0135Investigator Jennifer A. Kanakry, M.D. -
A Phase I/II Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 for HPV-Associated Cancers
Open - RecruitingNCI Protocol ID NCI-16-C-0154Investigator Christian S. Hinrichs, M.D. -
Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy Subjects for the Expansion of T Cells for Adoptive Cell Therapy
Open - RecruitingNCI Protocol ID NCI-16-C-0138Investigator Christian S. Hinrichs, M.D. -
Biospecimen Procurement for Experimental Transplantation and Immunology Branch Immunotherapy Protocols
Open - RecruitingNCI Protocol ID NCI-16-C-0061Investigator Christian S. Hinrichs, M.D. -
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
Open - RecruitingNCI Protocol ID NCI-16-C-0003Investigator Jennifer A. Kanakry, M.D. -
Autologous and Related Allogeneic Hematopoietic Stem Cell Transplant and Cellular Therapies Data Submission to the Center for International Blood and Marrow Transplant Research (CIBMTR) and the National Marrow Donor Program (NMDP)
Open - RecruitingNCI Protocol ID NCI-09-C-0053Investigator Ronald E. Gress, M.D.
PI & Key Staff
Positions
| Position | Keywords | Contact Name | Contact E-mail | Number of Positions |
|---|---|---|---|---|
| Postdoctoral Fellow- Cell Therapy/Hematopoietic Cell Transplantation |
immunology, immunotherapy, transplantation |
Christopher Kanakry | 1 |
Cores
ETIB Clinical Core
Personnel in this Core provide the infrastructural expertise for excellence in patient care and clinical research.
Judy L. Baruffaldi, Patient Care Coordinator (Contr.)
Tracey Chinn, RN, BSN, MPM, Head, Clinical Studies Unit
Sarfraz A. Memon, M.D., Research Chemist
Scott Napier, Physician Assistant
Eun Soo Paek, RN, BSN, Clinical Apheresis Nurse
Laura Skeffington, B.S., Physician Assistant (Contr.)
Anita Stokes, Nurse Practitioner
Jennifer Wilders, RN, Nurse Specialist (Contr.)
Contact Info
Center for Cancer Research
National Cancer Institute
Building 10, Room 3E3330
Bethesda, MD 20892-1203
Ph: 240-858-3030
Fax: 240-541-4566