Cristina Bergamaschi, Ph.D.
Staff Scientist

Center for Cancer Research
National Cancer Institute

Building 535, Room 226A
Frederick, MD 21702
301-846-1856

Dr. Bergamaschi's research focus is on the regulation of immunity in cancer and infectious disease. Her main project investigates the molecular biology of cytokines, in particular interleukin-15 (IL-15), and their role in lymphocyte homeostasis, with the ultimate goal of developing improved vaccine and immune therapy strategies for clinical applications.

Areas of Expertise
1) regulation of immunity, 2) cytokines, 3) IL-15

Dr. Bergamaschi's research focuses on the regulation of immunity in cancer and infectious disease. Her main project investigates the molecular biology of cytokines, in particular interleukin-15 (IL-15), and their role in lymphocyte homeostasis, with the ultimate goal of developing improved vaccine and immune therapy strategies for clinical applications.

Scientific Focus Areas:
Immunology
Selected Key Publications
  1. Bergamaschi C, Rosati M, Jalah R, Valentin A, Kulkarni V, Alicea C, Zhang GM, Patel V, Felber BK, Pavlakis GN.
    J Biol Chem. 283: 4189-99, 2008. [ Journal Article ]
  2. Bergamaschi C, Jalah R, Kulkarni V, Rosati M, Zhang GM, Alicea C, Zolotukhin AS, Felber BK, Pavlakis GN.
    J Immunol. 183: 3064-72, 2009. [ Journal Article ]
  3. Rosati M, Bergamaschi C, Valentin A, Kulkarni V, Jalah R, Alicea C, Patel V, von Gegerfelt AS, Montefiori DC, Venzon DJ, Khan AS, Draghia-Akli R, Van Rompay KK, Felber BK, Pavlakis GN.
    Proc Natl Acad Sci USA. 106: 15831-6, 2009. [ Journal Article ]
  4. Bergamaschi C, Bear J, Rosati M, Beach RK, Alicea C, Sowder R, Chertova E, Rosenberg SA, Felber BK, Pavlakis GN.
    Blood. 120: e1-8, 2012. [ Journal Article ]
  5. Chertova E, Bergamaschi C, Chertov O, Sowder R, Bear J, Roser JD, Beach RK, Lifson JD, Felber BK, Pavlakis GN.
    J Biol Chem. 288: 18093-103, 2013. [ Journal Article ]

Dr. Cristina Bergamaschi received her Ph.D. in molecular medicine specializing in immunology from the University of Milan, Italy, in 2008. After postdoctoral training in the Human Retrovirus Section, Vaccine Branch, NCI, Dr. Bergamaschi joined the Human Retrovirus Pathogenesis Section, Vaccine Branch, as a staff scientist in 2012.

Summary

Dr. Bergamaschi's research focus is on the regulation of immunity in cancer and infectious disease. Her main project investigates the molecular biology of cytokines, in particular interleukin-15 (IL-15), and their role in lymphocyte homeostasis, with the ultimate goal of developing improved vaccine and immune therapy strategies for clinical applications.

Areas of Expertise
1) regulation of immunity, 2) cytokines, 3) IL-15

Research

Dr. Bergamaschi's research focuses on the regulation of immunity in cancer and infectious disease. Her main project investigates the molecular biology of cytokines, in particular interleukin-15 (IL-15), and their role in lymphocyte homeostasis, with the ultimate goal of developing improved vaccine and immune therapy strategies for clinical applications.

Scientific Focus Areas:
Immunology

Publications

Selected Key Publications
  1. Bergamaschi C, Rosati M, Jalah R, Valentin A, Kulkarni V, Alicea C, Zhang GM, Patel V, Felber BK, Pavlakis GN.
    J Biol Chem. 283: 4189-99, 2008. [ Journal Article ]
  2. Bergamaschi C, Jalah R, Kulkarni V, Rosati M, Zhang GM, Alicea C, Zolotukhin AS, Felber BK, Pavlakis GN.
    J Immunol. 183: 3064-72, 2009. [ Journal Article ]
  3. Rosati M, Bergamaschi C, Valentin A, Kulkarni V, Jalah R, Alicea C, Patel V, von Gegerfelt AS, Montefiori DC, Venzon DJ, Khan AS, Draghia-Akli R, Van Rompay KK, Felber BK, Pavlakis GN.
    Proc Natl Acad Sci USA. 106: 15831-6, 2009. [ Journal Article ]
  4. Bergamaschi C, Bear J, Rosati M, Beach RK, Alicea C, Sowder R, Chertova E, Rosenberg SA, Felber BK, Pavlakis GN.
    Blood. 120: e1-8, 2012. [ Journal Article ]
  5. Chertova E, Bergamaschi C, Chertov O, Sowder R, Bear J, Roser JD, Beach RK, Lifson JD, Felber BK, Pavlakis GN.
    J Biol Chem. 288: 18093-103, 2013. [ Journal Article ]

Biography

Dr. Cristina Bergamaschi received her Ph.D. in molecular medicine specializing in immunology from the University of Milan, Italy, in 2008. After postdoctoral training in the Human Retrovirus Section, Vaccine Branch, NCI, Dr. Bergamaschi joined the Human Retrovirus Pathogenesis Section, Vaccine Branch, as a staff scientist in 2012.