Staff Scientist - TGFbeta, cancer metastasis

Staff Name: 
Li Yang, Ph.D.
Laboratory of Cancer Biology and Genetics
Research Area Keywords: 

cancer biology, immunology, molecular biology, metastasis, TGFbeta, immune microenvironment 

Position Description: 

The Center for Cancer Research (CCR) is working to solve the most pressing problems in the field through basic, translational and clinical cancer research to create the cancer medicines of tomorrow and is dedicated to preparing the next generation of cancer researchers. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences. 

Our scientists can’t do it alone. It takes a skilled, multi-disciplinary team of dedicated staff in research, patient care and administration to improve the lives of cancer patients and answer the most important questions in cancer biology and treatment. Be part of our mission to unlock the mysteries of cancer through research to create the medicines of tomorrow.

A staff scientist position is available immediately in the Laboratory of Cancer Biology and Genetics, Tumor Microenvironment Section, CCR, National Cancer Institute, Bethesda, Maryland, for a highly experienced scientist to investigate at least one of the topics below, and to train and supervise graduate students and junior postdoctoral fellows.

The projects in the Tumor Microenvironment Section include a) epithelial and myeloid TGF-beta signaling in breast cancer metastasis; b) mechanisms of TGF-beta regulation of inflammatory response systemically, in the tumor microenvironment and metastatic organ sites; c) single cell RNA sequencing of immune cell subsets in breast cancer metastatic progression; d) modulation of immune cell subsets in vivo using pharmacological and genetic approaches; e) targeted therapy and immunotherapy in preclinical mouse models of breast cancer metastasis; and f) myeloid TGF-beta signaling and inflammatory stroke.

Number of Positions: 
C.V. Required: 
Number of References Required: 
Experience Required: 

Eligible candidates must have a Ph.D., M.D., or equivalent doctoral degree in cancer biology, immunology, and molecular biology. The position will require at least five (5 ) years of experience in cancer biology and immunology, excellent publication record and expertise in at least one of the following areas: TGF-beta signaling, single cell RNA-seq analysis, creation of conditional gene-knockout mice and experimental cancer models, and epigenetics. The candidate is also expected to show ability and experience to train and supervise junior fellows.    

Additional Information: 

Bethesda, located adjacent to Washington, D.C., is an urban core of Montgomery County, MD. Bethesda is one of the most affluent and highly educated communities in the United States. Living in Bethesda offers residents a suburban feel with a lot of restaurants, coffee shops, and parks. The public schools in Bethesda are highly rated.

How To Apply: 

Please send cover letter, curriculum vitae, bibliography, and statement of research interest and list of 3 references to:

Li Yang, Ph.D.
Senior Investigator
Head, Tumor Microenvironment Section
Laboratory of Cancer Biology and Genetics
Center for Cancer Research, National Cancer Institute
37 Convent Drive, MSC 4258
Bethesda, MD 20892-4258

Contact Name: 
Li Yang
Contact E-mail: 
Contact Phone: 
Contact Fax: 

HHS, NIH, and NCI are Equal Opportunity Employers