Center for Cancer Research

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Staff Scientist - myeloid, splicing, hematopoiesis

Job Description:

Position is with:

The Center for Cancer Research (CCR), in the National Cancer Institute (NCI) invites applications for a Staff Scientist position in the Laboratory of Receptor Biology and Gene Expression (LRBGE), located in Bethesda, Maryland.  The candidate will work under the leadership of Dan Larson, Ph.D.. The primary goal of the Larson laboratory is to understand gene expression in eukaryotic cells, starting from the mechanistic behavior of individual macromolecules and proceeding to their regulation in cells and tissue. The laboratory utilizes a battery of biophysical and molecular approaches, including single-molecule microscopy, fluorescence fluctuation analysis, RNA visualization in fixed and living cells, single-cell RNA sequencing and computational modeling of gene regulation. Recent work is aimed at understanding gene expression in the context of hematopoiesis both in health and disease.

Qualifications and Job Details:

  • Degree Required: Ph.D. or equivalent
  • Location: Bethesda, Maryland
  • Appointment Type: Government Position
  • Work Schedule: Full-time position
  • Citizenship: US Citizenship not required - (ie, permanent resident, visa)
  • Salary: Commensurate with experience

REQUIRED SKILLS: The successful candidate will hold a Ph.D. degree or equivalent and have at least two years of post-doctoral experience with a strong background in gene regulation, cell biology, and hematopoiesis. While candidates with a wide range of expertise will be considered, applicants with a background in cell and molecular biology with a focus on hematopoiesis and myeloid malignancy are especially encouraged to apply. Anticipated methodologies include assessment of alternative splicing using genomic methods, generation of experimental model systems to recapitulate aspects of myeloid disease, carrying out biobanking and clinical correlates on patients enrolled in clinical trials, and proteo-genomic studies to correlate changes in gene expression in human samples.

PREFERRED SKILLS: Expertise in translational bench-to-bedside applications and immunobiology is especially preferred. The candidate will join an integrated team of bench and computational scientists with common research interests.

About the NCI Center for Cancer Research:

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.

How to Apply:

  • CV/Resume
  • Statement of Research Goals
  • Three References
  • Cover Letter
  • Summary of Research Experience

Additional Application Information:

Salary is commensurate with education and experience. Full Federal benefits including retirement, health and life insurance, annual and sick leave, long-term care insurance, and Thrift Savings Plan (401k equivalent) is available.  This position is not restricted to U.S. citizens. To apply, send a curriculum vitae and bibliography, a brief summary of research interests and accomplishments, scientific experience, and the names and addresses of three references to Dan Larson at

Contact Name: Dan Larson

Contact Email:

For questions contact: Dan Larson,

HHS, NIH, and NCI are Equal Opportunity Employers