Staff Scientist - Immunology, microbiology

The Center for Immuno-Oncology (CIO), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH) invites applications for a Staff Scientist position to lead the laboratory’s analysis of tumor immune micro-environment (TIME) in clinical samples of patients treated with immune-therapeutic agents.  This is an outstanding career opportunity in the NCI for a scientist who wishes to study the complex interaction between the tumor and immune cells and to find the key players for a successful therapeutic anti-tumor response using newly developed agents that target the immune system.  The laboratory is using state-of-the-art technologies for analysis of TIME including multiplexed multispectral imaging, single cell RNA-Seq and digital spatial transcriptomics. The staff scientist will oversee assays including scRNA-Seq, TIL analysis and digital spatial transcriptomics along with the TIME staff.  The staff scientist will use these tools to understand and characterize the tumor-immune cells interaction and study its evolution in primary and metastatic tumor and during treatment. The staff scientist will support the clinical team by defining biomarkers for patient selection/stratification, studying mechanism of action, etc.  This is a key leadership position in the James Gulley laboratory, located on the main NIH campus in Bethesda, Maryland and consisting of highly collaborative researchers. 

For more information, see Center for Immuno-Oncology.

Who We Are

The Center for Cancer Research (CCR) is the intramural research component of the NCI. CCR’s enabling infrastructure facilitates clinical studies at the NIH Clinical Center, provides extensive opportunities for collaboration, and allows scientists and clinicians to undertake high-risk, high- impact laboratory and clinically based investigations. Investigators are supported by a wide array of intellectual, technological and research resources including, animal facilities and dedicated, high-quality technology cores in areas such as imaging/microscopy, chemistry/purification, mass spectrometry, flow cytometry, genomics/DNA sequencing, transgenics and knockout mice, arrays/molecular profiling, and human genetics/bioinformatics. For an overview of CCR, please visit Center for Cancer Research.

Eligibility

The successful candidate must possess a Ph.D. degree in immunology, molecular biology, or related field and at least 3 years of post-doctoral research experience, and a strong publication record in cancer biology with an emphasis on immunology, oncology/immuno-oncology, transcriptomic analysis or similar.

Full Federal benefits including leave, health insurance, life insurance, long-term care insurance, retirement, and a Thrift Savings Plan (401k equivalent) will be provided.  Candidates may be U.S. citizens, U.S. permanent residents, or eligible for a visa that will enable work in the United States. This position is subject to a background investigation.

Selection for this position will be based solely on merit, with no discrimination for non-merit reasons such as race, color, religion, gender, sexual orientation, national origin, political affiliation, marital status, disability, age, or membership or non-membership in an employee organization. NIH encourages the application and nomination of qualified women, minorities, and individuals with disabilities. NIH provides reasonable accommodations to applicants with disabilities. If you require reasonable accommodation during any part of the application and hiring process, please notify us. The decision on granting reasonable accommodation will be made on a case-by-case basis. The NIH is dedicated to building a diverse community in its training and employment programs.  Salary and benefits are commensurate with research experience and accomplishments.