Staff Scientist - high-throughput imaging
High-Throughput Imaging, Functional Genomics Screening
The Center for Cancer Research (CCR) at the National Cancer Institute (NCI) invites applications for a Staff Scientist position in the High-Throughput Imaging Facility (HiTIF)/LRBGE. Qualified candidates will have a strong background and extensive experience in high-throughput image processing and analysis, machine learning, and deep learning. In this position, the Image Bioinformatics Scientist will drive the development and implementation of automated image and data processing workflows to analyze large image datasets generated by high-throughput confocal microscopes. These projects will involve researching innovative approaches for segmenting (sub) cellular structures from multi-dimensional optical images using state-of-the-art techniques (deep learning algorithms and graph-cuts), multi-modal image registration, feature extraction, unsupervised classification of phenotypic high-content/high-throughput imaging-based screens, and spatio-temporal analysis of single-cell level data. In addition, the successful candidate will be responsible for setting up and managing the HiTIF computational infrastructure. The Image Bioinformatics Scientist will work in a fast-paced research environment and will collaborate on a daily basis with molecular cell biologists. She/He is expected to be self-motivated and to demonstrate the willingness and ability to develop novel image analysis workflows.
The Center for Cancer Research (CCR) is working to solve the most pressing problems in the field through basic, translational and clinical cancer research to create the cancer medicines of tomorrow and is dedicated to preparing the next generation of cancer researchers. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.
Our scientists can’t do it alone. It takes a skilled, multi-disciplinary team of dedicated staff in research, patient care and administration to improve the lives of cancer patients and answer the most important questions in cancer biology and treatment. Be part of our mission to unlock the mysteries of cancer through research to create the medicines of tomorrow.
The successful candidate will hold a Ph.D. degree in either Image Processing, Computer Vision, Biomedical Engineering, or Quantitative Biophotonics; have at least three (3) years of post-doctoral experience and a strong publication record in the field. Previous hands-on experience in setting up and managing computational infrastructure for image analysis workflows in a shared environment is preferred. Salary is commensurate with education and experience. A full benefits package is available, including retirement, health insurance, life insurance, long-term care insurance, annual and sick leave, and Thrift Savings Plan (401k equivalent). This position is not restricted to U.S. citizens.
The CCR HiTIF is a shared resource for CCR and NIH Investigators. We work with them in a collaborative fashion to design and execute novel high-throughput, fluorescence microscopy-based imaging assays, which are used to identify and dissect the molecular mechanisms underlying a variety of physiological and pathological cellular processes. More importantly, we have a demonstrated successful record in developing cutting edge computational workflows on high-performance CPU and GPU batch clusters to study a variety of biological pathways involved in genome architecture, chromatin regulation, the DNA damage response, cancer and aging, among others. For more information, visit our webpage. CCR is the intramural research component of NCI. CCR’s enabling infrastructure facilitates clinical studies at the NIH Clinical Center, the world’s largest dedicated clinical research complex, and provides extensive opportunities for collaboration; and allows scientists and clinicians to undertake high-risk, high-impact laboratory- and clinic-based investigations. For an overview, please visit the CCR website.
Bethesda, located adjacent to Washington, D.C., is an urban core of Montgomery County, MD. Bethesda is one of the most affluent and highly educated communities in the United States. Living in Bethesda offers residents a suburban feel with a lot of restaurants, coffee shops, and parks. The public schools in Bethesda are highly rated.
The search will remain open until a qualified applicant is found. Consideration of applicants will begin on or around 9/1/2019. Interested individuals should send a brief cover letter, a CV/bibliography and the contact information for three references to:
Attn: Gianluca Pegoraro, Facility Head
High-Throughput Imaging Facility (HiTIF)
Laboratory of Receptor Biology and Gene Expression (LRBGE)
National Cancer Institute
HHS, NIH, and NCI are Equal Opportunity Employers