Staff Scientist - Cancer Genomics

Staff Name: 
Kenneth Aldape, M.D.
Laboratory of Pathology
Research Area Keywords: 

Cancer Genomics

Position Description: 

The Laboratory of Pathology (LP), Center for Cancer Research (CCR) of the National Cancer Institute (NCI), National Institutes of Health (NIH), is actively recruiting for a Staff Scientist to work in the area of cancer genomics and to participate in our expanding clinical genomic program. In particular, the LP has several NGS-based assays to identify genetic changes in clinical samples derived from cancer patients seen by the intramural program of the NCI. The Scientist will work with pathologists, bioinformaticians, wet lab scientists and support staff in the LP to analyze data and generate clinical pathology reports. This position represents an effort to build on the LP’s growing interest and expertise in both scientific discovery in cancer genomics and clinical application of genomic studies on human cancer specimens.

Research interests of the successful applicant may include investigation of the genetic and molecular landscape of a wide range of cancers as well as systematic genome-wide approaches to interrogate the function of cancer genes and the vulnerabilities of tumors. The incumbent will lead the effort that integrates high complexity cancer genomic testing into the clinic, by ensuring patient testing of the highest quality, incorporation of new assays based on recent research findings and reporting of actionable findings to physicians involved in the management of cancer patients. The future of cancer care is precision medicine. This is an exciting opportunity for an individual with interests in both cancer gene discovery and the application of high complexity testing such as next-generation sequencing and genome-wide array-based approaches in the clinical setting of diagnostic pathology. We are targeting an individual with experience and expertise in the analysis of alterations in cancer genes, epigenomics, gene expression and/or DNA copy number in human tumor specimens and model systems. In addition, experience in the clinical NGS workflow including assay development, validation, and other necessary steps required by accrediting bodies is required. Experience in designing and developing whole exome sequencing, RNA-seq, and targeted sequencing in clinical settings with multiple platforms and operational management is preferred. Emerging evidence indicates the utility of cancer genomic and epigenomic analysis to be contributory not only to specific therapeutic choices, but also to tumor classification and precision diagnostics. Integration of molecular alterations within the context of clinical cancer diagnostics represents an exciting direction that would be expected of the successful applicant.

CCR is working to solve the most pressing problems in the field through basic, translational and clinical cancer research to create the cancer medicines of tomorrow and is dedicated to preparing the next generation of cancer researchers. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences. 

Our scientists can’t do it alone. It takes a skilled, multi-disciplinary team of dedicated staff in research, patient care and administration to improve the lives of cancer patients and answer the most important questions in cancer biology and treatment. Be part of our mission to unlock the mysteries of cancer through research to create the medicines of tomorrow.

Number of Positions: 
C.V. Required: 
Experience Required: 

The successful candidate should have an M.D. or Ph.D. degree and a well-established track record of publications in the area of cancer genomics. The candidate will work closely with academic pathologists to help drive the correlative studies that will be an essential component of integrated genomic analyses. This is an exciting opportunity to join a growing trans-institutional, translational research team that will promote and support collaborations across the basic, translational, and clinical research spectrum as the field of diagnostic pathology navigates through the genomic era. The successful applicant will provide demonstratable leadership implementing cancer genomics into basic and/or translational research and be highly collaborative. Candidates will be evaluated on their educational background, scholarly work, leadership and mentoring activities and experience. Salary will be commensurate with education and experience. Candidates may be U.S. citizens, U.S. permanent residents or eligible for a visa that will enable work in the United States.

Additional Information: 

Bethesda, located adjacent to Washington, D.C., is an urban core of Montgomery County, MD. Bethesda is one of the most affluent and highly educated communities in the United States. Living in Bethesda offers residents a suburban feel with a lot of restaurants, coffee shops, and parks. The public schools in Bethesda are highly rated.

How To Apply: 

Please submit curriculum vitae and statement of research interests and future plans to: Ms. Issa Burguillos at Review of applications will begin on or about January 2, 2020 and the position will remain open until filled.

Contact Name: 
Issa Burguillos
Contact E-mail: 
Contact Phone: 

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