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Center for Cancer Research

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Staff Scientist - Cancer Biology, Immunology Biological Sciences

Job Description:

Position is with:

The Women's Malignancies Branch (WMB), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institute of Health (NIH) invites applicants for a full-time staff scientist position. This WMB is looking for a highly motivated individual with expertise in cell and molecular biology, animal experimentation, bioinformatics, and neuro-oncology and has very strong technical, oral, and written skills.

The laboratory conducts a translational research program that bridges preclinical murine models of metastasis studies with translation of projects for early phase clinical trials. Projects address aspects of brain metastasis of cancer including the blood-tumor barrier, pathways regulating metastatic colonization of the brain, immune involvement, and preclinical credentialing of potential preventive and therapeutic compounds.  

The successful candidate will lead a research team consisting of postdoctoral fellows, graduate students, biologists, as well as supporting animal technicians. The candidate must have a demonstrated background of collaboration with translational and clinical scientists. The individual will have strong logical/analytic thinking skills and expertise in laboratory management.

The incumbent staff scientist will have the primary responsibility of leading the planning and execution of research related to the study of brain metastasis. Projects include the (1) design of animal preclinical experiments, (2) analysis of animal tissues by standard histology and immunofluorescence staining and use of quantitative methods to determine expression trends; (3) analysis of immune infiltration into brains; (4) single-cell sequencing of selected in vitro and in vivo tissues; (5) tissue culture experience of cancer cell lines; molecular analyses of gene and protein expression using q-PCR and western blotting.  In addition, the staff scientist will supervise and train personnel, including biologists, pre-and post-doctoral fellows, and other junior research personnel. The candidate will participate in lab maintenance including the filing of animal study proposals and other regulatory requirements. The candidate will be expected to represent the WMB at national and international meetings.

Qualifications and Job Details:

  • Degree Required: Ph.D. or equivalent
  • Location: Bethesda, Maryland
  • Appointment Type: Government Position
  • Work Schedule: Full-time position
  • Citizenship: US Citizenship not required - (ie, permanent resident, visa)
  • Salary: Commensurate with experience

REQUIRED SKILLS:

Must possess a doctoral degree from an accredited university in cancer biology, immunology, biological sciences, cell biology, developmental biology, medical sciences, or the like, and have completed a post-doctoral fellowship and have experience in animal models, molecular and cellular biology, immunology, metastasis, translational research. Exceptional written and verbal skills and an ability to work cohesively in a multidisciplinary team environment are essential. Strong publication record and expertise in microenvironmental studies, immunology, cell therapy strongly preferred.

PREFERRED SKILLS:

Successful candidates should have a strong track record of publications demonstrating knowledge of both human and mouse cancer biology. A high degree of ability to work independently on multiple projects, complete projects with an acceptable timeline. Successful candidates should have a strong track record of publication. A high degree of ability to work independently on multiple projects, complete projects with acceptable timeliness and quality, and demonstrated the ability to work in a team and interact with scientists and clinicians in the intramural and extramural scientific communities. Previous hands-on experience in the use of single-cell sequencing and data analysis will be preferred.

About the NCI Center for Cancer Research:

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.

How to Apply:

Submit:
  • CV/Resume
  • Three References
  • Summary of Research Experience

Contact Name: Josselyn White

Contact Email: Josselyn.white@nih.gov

For questions contact: Josselyn White, Josselyn.white@nih.gov

HHS, NIH, and NCI are Equal Opportunity Employers