Center for Cancer Research

To improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care.

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Senior Investigator/Laboratory Chief (LCIM) - metabolic pathways, immune cell function, cancer

Job Description:

Position is with:

The National Cancer Institute (NCI) is seeking an outstanding, internationally recognized and visionary scientist to lead the newly established Laboratory of Cancer Immunometabolism (LCIM), in the Center for Cancer Research (CCR). This position is part of the National Institutes of Health’s (NIH) world-class intramural research program (IRP) and equivalent to a tenured academic department chair.

The LCIM is comprised of 10 independent Senior Investigators, who conduct research at the cellular, molecular, biochemical, and genetic level to unravel and exploit the metabolic interplay between host immune cells and developing or advancing cancers.  Investigators in LCIM explore the metabolic pathways regulating immune cell function and cancer progression, including their biochemical and cellular crosstalk in the context of unique anatomical, metabolic or immunological niches with the goal of ultimately determining disease risk and prognosis, as well as contributing to therapeutic drug development.  Further information about the LCIM may be found at:

The successful candidate will be appointed as a tenured NIH Senior Investigator and Laboratory Chief of the LCIM, and will lead her/his own individual world-class research program, supported by stable resources, including access to a wide range of NCI technology platforms and interdisciplinary collaborations within NCI as well as at NIH and its Clinical Center. In addition, the chief will provide scientific and administrative leadership to the LCIM by defining the overall scientific direction and identifying new research opportunities, including through recruitment of junior and senior faculty and management of lab/branch resources. The chief will also oversee mentoring and training activities and is responsible for ensuring an inclusive, diverse, collaborative and healthy work environment.

Qualifications and Job Details:

  • Degree Required: Ph.D. or equivalent
  • Location: Frederick, Maryland
  • Appointment Type: Government Position
  • Work Schedule: Full-time position
  • Citizenship: US Citizenship not required - (ie, permanent resident, visa)
  • Salary: Commensurate with experience

REQUIRED SKILLS: The successful candidate must have an established record in the field of immunometabolism, demonstrated leadership ability, proven effectiveness in mentoring and must meet the criteria for NIH tenure.

About the NCI Center for Cancer Research:

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Frederick is the second largest city in Maryland but retains a “small town” feel, surrounded by mountain views with a vibrant Main Street community. The city offers outstanding schools, a balanced and thriving economy and a highly educated workforce.

How to Apply:

  • CV/Resume
  • Statement of Research Goals
  • Cover Letter
  • Description of mentoring and outreach activities

Additional Application Information:

The current curriculum vitae must include a description of your mentoring and outreach activities, especially those involving women and persons from racial/ethnic and other groups that are underrepresented in biomedical research.

Contact Name: Lori Holliday

Contact Email:

For questions contact: Lori Holliday,

HHS, NIH, and NCI are Equal Opportunity Employers