brain tumor metabolism, metabolomics, Raman spectroscopy
The Neuro-Oncology Branch (NOB), Center for Cancer Research (CCR), National Cancer Institute (NCI) of the National Institutes of Health (NIH) is seeking outstanding postdoctoral candidates interested in studying the metabolic changes in brain tumors such as glioblastoma multiforme (GBMs). NOB’s Metabolomics program is interested in revealing the metabolic alterations of isocitrate dehydrogenase (IDH1)-mutated GBMs and in exploiting these deregulations for therapeutic applications. A combination of methods such as molecular biology, animal models, as well as in vitro and in vivo metabolomics using Raman Imaging Microscopy, Nuclear Magnetic Resonance spectroscopy (NMR), Mass Spectrometry (MS) and Magnetic Resonance Imaging (MRI) techniques are employed. The position will specifically focus on molecular biology and Raman Imaging Microscopy, which includes work in Western Blotting, mammalian cell culture and other common biomedical techniques used in cancer bio logy labs such as handling tissue samples, preparing tissue slides, staining, and extracting proteins from brain tissue.
Successful candidates should have 1) experience in handling cell culture and tissue, 2) experience in manipulating human cell lines such as neurospheres, different tissue, blood and urine samples, and 3) be highly independent in designing the experiments, analyzing the data and presenting the results. Applicants should have a Ph.D. and/or M.D., relevant experience highlighted above, and less than three years of postdoctoral experience.
Please email curriculum vitae, statement of research interests, and three letters of reference to the attention of:
Mioara Larion, Ph.D.
National Cancer Institute
37 Convent Drive
Building 37, Room 1136A
Bethesda, MD 20892
HHS, NIH, and NCI are Equal Opportunity Employers