Postdoctoral Fellow - nanobiology, cancer
exosomes, nanobiology, biochemistry, HPLC, flow cytometry
An opportunity is available to work within Jennifer Jones’s laboratory in the Translational Nanobiology Section, Laboratory of Pathology, Center for Cancer Research (CCR), National Cancer Institute (NCI). This is a postdoctoral fellow position to work as an integral member of the Translational Nanobiology Section. Our lab is developing a scalable, high-throughput, clinical pipeline to utilize extracellular vesicles as biomarkers. Extracellular vesicles (EVs) range in diameter from 30-1000 nm, our laboratory therefore continues to utilize, test, and develop cutting-edge analysis equipment and assays.
The project will focus on developing and leveraging new assays and methods of characterizing EVs and their cargo, including methods for single molecule detection for characterization of EVs in different types of cancer. This interdisciplinary project will include the development of single-molecule detection labels for single EV flow cytometry by functionalizing plasmonic nanoparticles with oligonucleotides. The candidate must have expertise in biochemistry, nanoparticle synthesis, high-performance liquid chromatography, and gel electrophoresis. Expertise in optics and experience using flow cytometry is desirable.
CCR is working to solve the most pressing problems in the field through basic, translational and clinical cancer research to create the cancer medicines of tomorrow and is dedicated to preparing the next generation of cancer researchers. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.
CCR is dedicated to preparing the next generation of cancer researchers and offers a training environment that is second-to-none in quality of science and mentoring by outstanding principal investigators, including nine members of the National Academy of Science and eight members of the National Academy of Medicine. CCR offers fellows access to cutting-edge technologies and cores, a highly collaborative environment, awards and research forums to recognize outstanding post docs, continuous scientific symposia and lectures featuring leading researchers, a strong commitment to translational research, and a vibrant clinical research program housed in the world’s largest dedicated research hospital, the NIH Clinical Center.
The ideal candidate will have a Ph.D. degree in cellular biology, biophysics, biochemistry, biomedical engineering, mechanical engineering, or a related discipline, with some background in molecular cell biology and conjugation chemistries, and a demonstrated ability to work in a multidisciplinary and diverse team. The candidate should have experience with nanomaterial synthesis, tissue culture, optical imaging, and programming for data analysis (preferably MATLAB, R, or Python). Strong communication and time management skills are also necessary. The ability to design and perform scientific work independently and collaboratively is required. Candidates must be motivated to join a fast-paced environment and will thrive while leading and carrying out studies in our Translational Nanobiology Section.
This position will enable the successful applicant to contribute to the conceptualization of multiple high-impact studies, to design and carry out experiments independently, to perform data analysis, and to write manuscripts for publication. Postdoctoral Fellows from our section not only are encouraged to participate in national and international conferences, but also are able to mentor summer interns and post-bacs when appropriate. Support for the Fellow’s career development will be a priority for the full duration of the postdoctoral fellowship.
Bethesda, located adjacent to Washington, D.C., is an urban core of Montgomery County, MD. Bethesda is one of the most affluent and highly educated communities in the United States. Living in Bethesda offers residents a suburban feel with a lot of restaurants, coffee shops, and parks. The public schools in Bethesda are highly rated.
Please contact laboratory manager Jason Savage at email@example.com with subject line "Postdoctoral Fellow - Chemistry". Include: CV, contact information for 3 references, brief (1/2 page) statement of interest.
HHS, NIH, and NCI are Equal Opportunity Employers