Postdoctoral Fellow - immunotherapeutics
thoracic malignancy, immunotherapeutics
A Post-doctoral Fellow position is available in the Thoracic Surgery Branch (TSB), Center for Cancer Research, National Cancer Institute, NIH.
Our broad goal is to explore the molecular and cellular biology of thoracic cancers, namely mesothelioma and/ or, thymoma, non-small cell lung carcinoma etc. Currently, we have projects that involve (1) investigating microRNA-mRNA interactions in malignant mesothelioma, (2) on the pathogenic signaling pathways relevant to tumor initiation, invasion, metastasis, and resistance, (3) novel local therapeutic delivery system(s) able to carry diverse types of payloads including nucleic acid, immunotherapeutics, targeted small molecule agents, or antibodies, as well as several other translational-based endeavors. For this recruitment, we seek to expand our immunotherapeutics development. With these projects, we have aims of developing novel molecular biomarkers and therapeutic targets based on an understanding of the pathogenetic mechanisms active in these cancers. The culmination of these projects will be linked to clinical human protocols in these thoracic cancers of interest.
This is a great opportunity for candidates who are generally interested in cancer biology and want to enhance their career potential by working in our research program with outstanding support of other established laboratories and core facilities in the National Cancer Institute. This laboratory effort will be in close collaboration with other faculty in our branch, within the NIH community at large and/ or extramural collaborators. We highly value a team-based approach. Individuals with self-motivation and willingness to collaborate will be most successful in this environment.
Qualified candidates should have a Ph.D. in a Biological science area or the equivalent background (M.D., M.B.B.S., etc) with one to five years of post-doctoral experience. A background and working knowledge in molecular and cellular biology is required and for this specific position we are seeking interest and/or experience in immunology. Other research backgrounds that may be a good fit include stem cell biology or RNA biology. Familiarity with basic techniques including DNA/ RNA isolation, cell culture techniques western-blot, quantitative PCR, immunohistochemistry, ChIP, retroviral or lentiviral transfections, CRISPR-Cas, FACS sorting, and working with mice are a must. Knowledge and/or experience in bioinformatics, biostatistics, mutation detection, microarray analysis, RNA-seq and other sequencing methodology, and microRNA is preferred.
Please submit a current curriculum vitae with statement of career goals, and three references with names/email addresses to: Jan.Pappas@nih.gov
HHS, NIH, and NCI are Equal Opportunity Employers