Job Description
A postdoctoral fellow position is available in the laboratory of Dr. Yuichi Machida in the Developmental Therapeutics Branch (DTB), National Cancer Institute (NCI), National Institutes of Health (NIH) to study DNA repair mechanisms and their effect on anti-cancer drug sensitivity. Dr. Machida’s research focuses on proteases involved in the repair of DNA-Protein Crosslink (DPC) damage. The successful candidate will study proteolytic DPC repair mechanisms using molecular and cellular biology techniques as well as mouse genetics. To learn more about the research in the Machida lab, please visit: https://ccr.cancer.gov/staff-directory/yuichi-machida.
The DTB offers a collaborative and highly interactive research environment. Opportunities are available to interact with members of the multidisciplinary research community in the Branch, which includes basic research scientists, bioinformaticians and clinical scientists. We are committed to creating an inclusive research environment and supporting the successful research careers of all our trainees.
Qualifications and Job Details
Required and Preferred Skills
Qualified candidates must have a Ph.D. in a field deemed relevant by the program before the appointment.
Candidates with a background in DNA repair or experience in the following areas are encouraged to apply:
- Structural biology
- Mouse studies
- Genomics
- Proteomics
- CRISPR screening
- Genome editing
- Single-molecule studies
- Assay development
About the NCI Center for Cancer Research
The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.
Bethesda
Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.