Postdoctoral Fellow - Cilia, Cell Biology

Staff Name: 
Christopher J. Westlake, Ph.D.
Lab/Branch/Program: 
Laboratory of Cell and Developmental Signaling
Location: 
Frederick
Research Area Keywords: 

Cilia, Cell Biology, Microscopy, Membrane Trafficking, Cancer

Position Description: 

The Center for Cancer Research (CCR) is working to solve the most pressing problems in the field through basic, translational and clinical cancer research to create the cancer medicines of tomorrow and is dedicated to preparing the next generation of cancer researchers. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

The NCI CCR is dedicated to preparing the next generation of cancer researchers and offers a training environment that is second-to-none in quality of science and mentoring by outstanding principal investigators, including nine members of the National Academy of Science and eight members of the National Academy of Medicine. CCR offers fellows access to cutting-edge technologies and cores, a highly collaborative environment, awards and research forums to recognize outstanding post docs, continuous scientific symposia and lectures featuring leading researchers, a strong commitment to translational research, and a vibrant clinical research program housed in the world’s largest dedicated research hospital, the NIH Clinical Center.

A post-doctoral position is available immediately in Dr. Christopher Westlake’s laboratory at the National Cancer Institute in Frederick Maryland. The major focus of the Westlake laboratory is investigating membrane trafficking regulators in primary and motile cilia function (e.g., Walia et al., Dev. Cell. 50:229-246, 2019; Insinna et al., Nat Commun. 10:919, 2019; Lu et al., Nat. Cell Biol. 17:228-240, 2015). Defects in cilia formation and function are associated with a growing number of human diseases and cancer. Our group combines cell biological, biophysical, biochemistry and proteomics, and genomics approaches to understand ciliary membrane trafficking mechanisms using cell line, zebrafish and mouse models. We offer excellent training opportunities in advanced fluorescence and electron microscopy imaging and analysis, including super resolution SIM/STORM/STED microscopy, live cell spinning disk confocal and lattice light sheet microscopy, transmission electron microscopy, and 3-D volumetric electron microscopy using FIB-SEM. Please visit our website for more information: https://ccr.cancer.gov/Laboratory-of-Cell-and-Developmental-Signaling/christopher-j-westlake

Number of Positions: 
1
C.V. Required: 
Yes
Number of References Required: 
3
Experience Required: 

We are looking for enthusiastic, imaginative and dedicated scientists with a strong interest in membrane trafficking, cilia biology and/or signal transduction to join our research team. The candidate must be highly motivated to participate in rigorous and innovative research programs, possess an excellent work ethic, have outstanding interpersonal/communication skills, and be able to work independently and collaborate closely with members of the group and other labs on joint projects. A strong background in molecular, cellular, or developmental biology is required. Research experience applying advanced microscopy-based approaches will be considered advantageous. Interested candidates should have a Ph.D. and/or an M.D. and have less than 4 years postdoctoral experience and a track record of productivity.

Additional Information: 

Our laboratory is located within The Laboratory of Cell and Developmental Signaling (LCDS) group, and is a part of the Cancer, Genetics and Signaling (CGS) Program.  More information on LCDS can be found at https://ccr.cancer.gov/Laboratory-of-Cell-and-Developmental-Signaling and on CGS at https://ccr.cancer.gov/training/specialized/cancer-genetics-signaling-fellows.

 

This position is located at CCR’s campus in Frederick, Maryland.  Frederick is the second largest city in Maryland but retains a “small town” feel, surrounded by mountain views, wineries, orchards and a vibrant Main Street community.  It is less than an hour’s drive from the NIH main campus as well as the Appalachian Trail, Washington, D.C., Baltimore, and Gettysburg. The city offers many outstanding schools, a balanced and thriving economy and a highly educated workforce.

How To Apply: 

Please email a cover letter with a brief description (1-2 pages) of past research and preferred start date, CV, and contact information for at least three professional references to chris.westlake@nih.gov.  Please write “Postdoctoral application” in the subject heading.

Contact Name: 
Christopher Westlake
Contact E-mail: 
Contact Phone: 
301-846-7594
Contact Fax: 
301-846-1666

HHS, NIH, and NCI are Equal Opportunity Employers