Postdoctoral Fellow - cell biology, ubiquitin
cell biology, ubiquitin, protein degradation, ERAD
A fully-funded postdoctoral position is available immediately in the Weissman lab in the Laboratory of Protein Dynamics and Signaling (LPDS), Center for Cancer Research, National Cancer Institute. Our focus on proteostasis includes regulated protein degradation and cellular quality control mechanisms involving the ubiquitin-proteasome system (UPS) particularly in the secretory pathway and mitochondria. We are especially interested in these as they relate to cellular stress, cancer and metastasis as well as cardiovascular disease. An additional area of interest is on structure-function relationships for RING-type ubiquitin protein ligases (E3s) and their interactions with ubiquitin conjugating enzymes (E2s). For more information, please see the Weissman website at https://ccr.cancer.gov/Laboratory-of-Protein-Dynamics-and-Signaling/allan-m-weissman.
Applicants should be completing, or have recently completed, a PhD or have an MD with limited relevant post-doctoral training. Appointees may be U.S. citizens, U.S permanent residents, or non-US residents eligible to obtain a valid employment authorization visa.
Applicants for this position should have a working knowledge of the ubiquitin-proteasome system and demonstrated expertise in biochemistry and cell biology. Applicants should also have an interest in working with, and potentially developing, animal models related to the ubiquitin-proteasome system and cancer. Experience in DNA manipulation as well as plasmid and siRNA transfection is a plus.
Fellows in LPDS interact extensively with other scientists on both the Frederick and Bethesda campuses of NIH as well as with collaborators at other institutions. The Frederick campus offers a highly collegial and collaborative environment with easy access to a wide range of advanced technologies.
Applicants should submit a cover letter, CV/Bibliography and names of three references to Allan Weissman at email@example.com. Please write “Postdoctoral application” in the subject line.
HHS, NIH, and NCI are Equal Opportunity Employers