Center for Cancer Research

To improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care.

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Post-doctoral Fellow - RNA Biology, Functional Transcriptomics

Job Description:

Position is with:

Fully funded postdoctoral research positions are available in Thomas Gonatopoulos-Pournatzis' Functional Transcriptomics Section within the RNA Biology Laboratory at the Center for Cancer Research (CCR), National Cancer Institute (NCI). The research of the group is focused on developing and applying exon-resolution CRISPR-based phenotypic screens to uncover splicing regulatory mechanisms that underlie biological complexity and, when disrupted, contribute to diseases including cancer and neurodevelopmental disorders.

These projects will afford the postdoctoral fellow with the unique opportunity to develop and apply cutting-edge technologies, including high-throughput CRISPR screening strategies, and to be part of a highly collaborative research environment in a newly equipped lab with state-of-the-art core facilities including, but not limited to, next-generation sequencing, mass spectrometry and imaging. The candidate will be fully funded by a competitive intramural fellowship. However, application for fellowship opportunities outside NIH are encouraged and supported. For more information about our research, please visit the Gonatopoulos-Pournatzis website at:

Qualifications and Job Details:

  • Degree Required: Ph.D. or equivalent
  • Location: Frederick, Maryland
  • Appointment Type: Training Position
  • Work Schedule: Full-time position
  • Citizenship: US Citizenship not required - (ie, permanent resident, visa)
  • Stipend: Commensurate with experience

REQUIRED SKILLS: Applicants must have less than three years postdoctoral experience. Applicants must have expertise in molecular biology, genetics, biochemistry, cell biology or bioinformatics. Applications from international candidates eligible to obtain a valid employment authorization visa are very much welcomed. Applicants with research experience in RNA biology, CRISPR technology, molecular biology and bioinformatics are especially encouraged to apply.

About the NCI Center for Cancer Research:

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Frederick is the second largest city in Maryland but retains a “small town” feel, surrounded by mountain views with a vibrant Main Street community. The city offers outstanding schools, a balanced and thriving economy and a highly educated workforce.

How to Apply:

  • CV/Resume
  • Three References
  • Cover Letter

Contact Name: Thomas Gonatopoulos-Pournatzis

Contact Email:

For questions contact: Thomas Gonatopoulos-Pournatzis,

HHS, NIH, and NCI are Equal Opportunity Employers