Center for Cancer Research

To improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care.

Join us!

Post-doctoral Fellow - immunology, breast cancer, therapy

Job Description:

Position is with:

Dr. St. Croix’s laboratory at the Mouse Cancer Genetics Program (MCGP), CCR, NCI, has an open postdoctoral position. We seek a highly motivated, creative and bright individual to participate in a collaborative project that involves genetic engineering and various other cutting-edge new technologies to selectively target tumor-associated stroma using antibody drug conjugates (ADCs), while minimizing off-target toxicities.  The laboratory focuses on the characterization and exploitation of molecules associated with tumor angiogenesis. The successful candidate would be involved in developing, producing and characterizing new therapeutic ADCs that recognize cancer cells or its associated stroma, and preclinical testing of these agents using mouse tumor models. This project is highly collaborative and will involve working closely with medicinal chemists who will help with the engineering and synthesis of optimized ADC payloads.  The tumor angiogenesis lab is located at the National Cancer Institute in Frederick with access to state-of-the-art facilities for antibody engineering, genomic analysis, pathology, and small animal imaging, among others.

Qualifications and Job Details:

  • Degree Required: Ph.D. or equivalent
  • Location: Frederick, Maryland
  • Appointment Type: Training Position
  • Work Schedule: Full-time position
  • Citizenship: US Citizenship not required - (ie, permanent resident, visa)
  • Stipend: Commensurate with experience


Candidates are expected to have completed, or be completing, a Ph.D. or M.D./Ph.D. in biomedical research with a strong publication record and expertise in molecular and cell biological techniques.  Motivated candidates who are interested in innovative, high-impact research are encouraged to apply.


A background in molecular biology, cancer biology or immunotherapy is preferred. Experience with antibodies or antibody drug conjugates (ADCs) is a big plus.

About the NCI Center for Cancer Research:

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Frederick is the second largest city in Maryland but retains a “small town” feel, surrounded by mountain views with a vibrant Main Street community. The city offers outstanding schools, a balanced and thriving economy and a highly educated workforce.

How to Apply:

  • CV/Resume
  • Statement of Research Goals
  • Three References

Additional Application Information:

Interested applicants should send their curriculum vitae, a brief description of their research interests and career goals, and contact information for three references to Dr. Brad St. Croix by email to

Contact Name: Brad St. Croix

Contact Email:

For questions contact: Brad St. Croix,

HHS, NIH, and NCI are Equal Opportunity Employers