The laboratory of David Takeda in the Center for Cancer Research at the National Cancer Institute is seeking a postdoctoral fellow interested in studying the role of epigenetic reprogramming in cancer. Starting date is flexible.
About the Takeda laboratory: The lab uses observations generated from clinical biospecimens such as surgical biopsies or circulating cell free DNA, to guide the development of functional studies in model systems. We combine genome-scale profiling methods such as ChIP-seq and ATAC-seq with functional genomics including pooled CRISPR-Cas9 screening approaches.
About the role: The fellow will have opportunities to generate genomic and epigenomic data from clinical samples to design and perform functional mechanistic studies in model systems such as patient derived organoids. The fellow will gain experience in genome-scale profiling methods, genome editing, and CRISPR-based genetic screening. Training in experimental and computational biology will be tailored to meet the goals and interests of the candidate. By having access to the nation’s largest hospital totally dedicated to clinical research, there are opportunities to study different stages of cancer including disease progression, drug resistance, and tumor immune response.
Qualifications and Job Details
Required and Preferred Skills
Candidates should have a Ph.D. or equivalent in biological sciences or related field prior to starting date. Experience in cancer biology and epigenomics is useful but not required.
About the NCI Center for Cancer Research
The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.
Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.
Interested applicants should submit a curriculum vitae, summary of current and future research interests, expected availability date, and three references to email@example.com.