Center for Cancer Research

To improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care.

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Post-doctoral Fellow - Cbl, TRAIL, ClpP agonist

Job Description:

Position is with:

The Lipkowitz laboratory of the Women's Malignancies Branch is looking for a Postdoctoral Fellow. The laboratory investigates signal transduction pathways that regulate growth and programmed cell death in epithelial cancer cells. The ongoing laboratory projects are: 1) Regulation of signaling by Cbl proteins; 2) Activation of TRAIL death receptor pathways to kill breast cancer cells; and 3) CLPP agonists as treatment for breast cancer. Each project has basic and translational components.

The open postdoctoral position is focused on developing inhibitors of Cblb, including small molecule inhibitors and PROTACs.

Qualifications and Job Details:

  • Degree Required: Ph.D. or equivalent
  • Location: Bethesda, Maryland
  • Appointment Type: Training Position
  • Work Schedule: Full-time position
  • Citizenship: US Citizenship not required - (ie, permanent resident, visa)
  • Stipend: Commensurate with experience


Laboratory experience with cell and molecular biology techniques.

About the NCI Center for Cancer Research:

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.

How to Apply:

  • CV/Resume
  • Statement of Research Goals
  • Summary of Research Experience

Contact Name: Stanley Lipkowitz

Contact Email:

For questions contact: Stanley Lipkowitz,

HHS, NIH, and NCI are Equal Opportunity Employers