Center for Cancer Research

To improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care.

Join us!

Post-doctoral Fellow - biomaterials, immunology, organoid, tissue engineering

Job Description:

Position is with:

The Cancer Biomaterials Engineering Section, LCIM, CCR, NCI is now hiring postdocs and postbacs for research in immunomodulatory biomaterials for cancer immunotherapy. The lab is led by Dr. Matthew Wolf, and is a multidisciplinary combination of biomaterials science, cancer immunology, and tissue engineering. Biomaterials are rapidly being developed as cancer immunotherapy delivery vehicles, tissue engineering scaffolds for cancer patients, scaffolds for tumor modeling, and as inflammatory regulators in cancer vaccines. The Wolf lab’s objective is to decode the fundamental immunological processes at the biomaterial-tissue interface to facilitate designing the optimal biomaterials for cancer immunotherapy applications.

The Wolf lab studies both decellularized-tissue and synthetic polymer biomaterials as immune regulators in cancer. These are applied to three focus areas:

(1)      Tumor extracellular matrix scaffolds for patient-specific organoid tumor modeling.

(2)      Biophysical biomaterial regulation of anti-tumor immune function.

(3)      The biomaterial chronic foreign body reaction in cancer immunity.

Qualifications and Job Details:

  • Degree Required: Ph.D. or equivalent
  • Location: Frederick, Maryland
  • Appointment Type: Training Position
  • Work Schedule: Full-time position
  • Citizenship: US Citizenship not required - (ie, permanent resident, visa)
  • Stipend: Commensurate with experience

REQUIRED SKILLS: Postdoc applicants are expected to hold an advanced degree (M.D., Ph.D or M.D./Ph.D.) in Biomedical Engineering, Immunology, Chemical Engineering, Cancer Biology, Materials Science, or related fields. Those with expected graduation dates in 2020/early 2021 may also apply.

PREFERRED SKILLS: Applicants with experience in the following area are strongly encouraged to apply: • Immunology / cancer immunology • Organoids / 3D culture models • Biomaterial scaffold design and characterization • Cell characterization (e.g. IHC and flow cytometry) • Proteomics • Transplantable tumor models and injury models in vivo • Tissue engineering

About the NCI Center for Cancer Research:

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Frederick is the second largest city in Maryland but retains a “small town” feel, surrounded by mountain views with a vibrant Main Street community. The city offers outstanding schools, a balanced and thriving economy and a highly educated workforce.

How to Apply:

  • CV/Resume
  • Statement of Research Goals
  • Three References

Contact Name: Matthew Wolf

Contact Email:

For questions contact: Matthew Wolf,

HHS, NIH, and NCI are Equal Opportunity Employers