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Center for Cancer Research

To improve the lives of cancer patients by solving important, challenging and neglected problems in cancer research and patient care.

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Post-baccalaureate Fellow - RNA biology, ribosome

Job Description:

Position is with:

Post-baccalaureate fellow positions are available in the field of RNA biology, molecular biology, biochemistry, and bioinformatics in Dr. Colin Wu’s Translational Control of Gene Expression section within the RNA Biology Laboratory at the Center for Cancer Research, National Cancer Institute in Frederick, Maryland. The major focus of the laboratory is to investigate molecular mechanisms of translational regulation and non-canonical functions of the ribosome in mammalian systems.

Multiple projects are available: (1) developing and applying high-throughput sequencing approaches to characterize in vivo dynamics of the ribosome and RNA-binding proteins; (2) exploring non-canonical functions of the ribosome in signal transduction; (3) characterizing local translation-coupled RNA decay and protein quality control. The position offers rigorous training opportunities in multiple disciplines to build a new high impact research program.

Recent relevant publications:

1. Ribosome collisions trigger general stress responses to regulate cell fate. Cell. 2020

2. High-resolution ribosome profiling defines discrete ribosome elongation states and translational regulation during cellular stress. Mol Cell. 2019

3. eIF5A functions globally in translation elongation and termination. Mol Cell. 2017

Qualifications and Job Details:

  • Degree Required:
    • B.S./B.A. or equivalent
    • Masters
  • Location: Frederick, Maryland
  • Appointment Type: Training Position
  • Work Schedule: Full-time position
  • Citizenship: US Citizenship required
  • Stipend: Commensurate with experience

REQUIRED SKILLS:

Prior wet lab experience is preferred.

About the NCI Center for Cancer Research:

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.

Frederick is the second largest city in Maryland but retains a “small town” feel, surrounded by mountain views with a vibrant Main Street community. The city offers outstanding schools, a balanced and thriving economy and a highly educated workforce.

How to Apply:

Submit:
  • CV/Resume
  • Statement of Research Goals
  • Two References
  • Cover Letter
  • Summary of Research Experience

Additional Application Information:

Applicants should send a brief cover letter, CV/resume, and contact information of two references to Dr. Colin Wu: colin.wu2@nih.gov. Candidates will be required to submit a full application at the NIH training portal (https://www2.training.nih.gov/apps/publicForms/pbt/forms/login.aspx) for full consideration.

Contact Name: Colin Wu

Contact Email: colin.wu2@nih.gov

For questions contact: Colin Wu, colin.wu2@nih.gov

HHS, NIH, and NCI are Equal Opportunity Employers