Investigator/Senior Investigator - pediatric oncology

Pediatric Oncology Branch
Research Area Keywords: 

pediatric refractory solid tumor, brain tumor, leukemia

Position Description: 

The CCR is a unique place of science where we combine diverse expertise with the freedom to thoroughly pursue the most pressing questions in cancer biology and treatment. The CCR is home to an extraordinary group of scientists and clinicians exploring the cutting-edge of cancer and HIV/AIDS research. Our scientists work on a wide spectrum of biological and biomedical problems enjoying complete intellectual freedom and are expected to creatively and innovatively explore the most important questions in the field of cancer research and treatment.  We support projects over a long-time horizon allowing our investigators to pursue some of the most difficult, high-risk problems in the field, offering a wide array of intellectual and technological and research resources.

The National Cancer Institute (NCI), National Institutes of Health (NIH), Department of Health and Human Services (DHHS) is seeking an outstanding scientist or physician scientist as a tenure track or tenure-eligible investigator in the Pediatric Oncology Branch (POB) at the Center for Cancer Research (CCR), National Cancer Institute. The POB is dedicated to improving the survival and quality of life for children and young adults with refractory solid tumors, brain tumors, leukemias, and genetic tumor predisposition syndromes. Building on the development of historic ground-breaking effective treatments for pediatric lymphomas, HIV, and sarcomas, the POB more recently has developed a focus on targeted therapies for solid tumors including brain tumors, and “first-in-human and first-in-children” cell-based therapies for relapsed acute lymphoblastic leukemias and solid tumors. In addition, the POB has an active trials program for genetic tumor predisposition syndromes such as neurofibromatosis type 1, hereditary medullary thyroid carcinoma, and succinate dehydrogenase-deficient tumors.  POB laboratory investigations focus on basic and tumor immunology, genomics, microenvironment, hemato-metabolism, and molecular alterations to develop a comprehensive understanding of the pathogenesis and progression of pediatric tumors and improve detection, diagnosis, classification and treatment of pediatric tumors.  The POB has an accredited joint fellowship training program with Johns Hopkins University, is a member of cooperative groups such as the Children’s Oncology Group and has collaborative initiatives with academic as well as industrial partners.

The National Cancer Institute is part of the National Institutes of Health in the Department of Health and Human Services, a federal government agency. The CCR is the largest component of the intramural biomedical research effort at NIH and a major user of the NIH Clinical Center, a state-of-the-art research hospital on the campus of NIH in Bethesda, Maryland. CCR, as a world-leading catalyst for tomorrow’s cancer research and patient treatments, offers a tremendous depth and breadth of intellectual and technological resources, as well as opportunities for collaboration with investigators both within and outside of the NIH. The NIH Clinical Center and CCR infrastructure allow for rapid translation from the bench to bedside and back and for the conduct of high-risk research, which require sustained commitment. The research environment is highly conducive to advancing translational research and highly collaborative, emphasizing multidisciplinary and interdisciplinary team science.

Further information about the Pediatric Oncology Branch may be found at:

Salary will be commensurate with experience.

Number of Positions: 
C.V. Required: 
Number of References Required: 
Experience Required: 

The successful candidate should conduct cutting-edge laboratory or translational research and have the ability and desire to work collaboratively with Pediatric Oncology Branch (POB) members on solving the most difficult problems.  The candidate must have a Ph.D. and/or M.D. degree or equivalent, and have an established record in research applicable to pediatric oncology, such as immunology, immunotherapy, or precision therapy.  Appointees may be U.S. citizens, resident aliens, or non-resident aliens with, or eligible to obtain, a valid employment-authorization visa.  

Additional Information: 

Bethesda, located adjacent to Washington, D.C., is an urban core of Montgomery County, MD. Bethesda is one of the most affluent and highly educated communities in the United States. Living in Bethesda offers residents a suburban feel with a lot of restaurants, coffee shops, and parks. The public schools in Bethesda are highly rated. 

How To Apply: 

Interested applicants should submit:

  • A letter of interest in the position including a career synopsis (1-3 pages)
  • A statement of research interests (1-2 pages)
  • A current curriculum vitae and complete bibliography

Please include in your CV a description of mentoring and outreach activities in which you have been involved, especially those involving women and persons from racial/ethnic or other groups that are underrepresented in biomedical research.

Applications must be submitted electronically to:

Review of applications will begin on or about October 28, 2019, but applications will be accepted until the position is filled.

For questions regarding the application process, please contact Jennifer Dreier at

Contact Name: 
Jennifer Drier
Contact E-mail: 

HHS, NIH, and NCI are Equal Opportunity Employers