The Laboratory of Pathology, Center for Cancer Research (CCR) of the National Cancer Institute (NCI), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Bethesda, MD, is actively recruiting for a staff clinician to participate in the Laboratory of Pathology’s expanding clinical cancer genomics program. In particular, this individual will contribute to the direction of next-generation sequencing and/or genome-wide array-based clinical platforms. This position represents an effort to augment the current capabilities in molecular diagnostics and to build on the Laboratory of Pathology’s growing interest and expertise in clinical cancer genomics and precision diagnostics. This is an exciting opportunity for an individual with interests and expertise in the application of next-generation sequencing and genome-wide array-based approaches in the clinical setting of diagnostic pathology. Emerging evidence indicates that cancer genomic and epigenomic analysis is contributory not only to specific therapeutic choices, but also to tumor classification and precision diagnostics. Current clinical NGS platforms include a 500-gene panel (TSO-500), whole-transcriptome RNAseq for fusion detection, and whole exome sequencing for somatic mutations. Plans are also underway to validate a 500-gene liquid biopsy assay for clinical reporting. Integration of molecular alterations within the context of standard anatomic pathology diagnostic workflow represents an exciting direction that is being vigorously pursued by the Laboratory of Pathology and provides many opportunities for involvement by the successful applicant.
Qualifications and Job Details
Required and Preferred Skills
The ideal candidate will have an MD and/or PhD, will be clinically trained in pathology or genetics, and will be board certified/board eligible by the American Board of Pathology or the American Board of Medical Genetics and Genomics. Practical experience in sign-out and development of next generation sequencing or genome-wide array-based assays will be prioritized. Individuals at all levels of experience are welcome to apply, and leadership activities in our molecular diagnostic program will be based on interests and experience of the candidate. This individual will work closely with other molecular pathologists as well as surgical pathologists, clinical oncologists and cancer biologists to help drive the correlative studies that will be an essential component of integrated clinical cancer genomic analyses. This is an exciting opportunity to join a growing trans-institutional, translational research team that will promote and support collaborations across the basic, translational, and clinical research spectrum as the field of diagnostic pathology navigates through the genomic era.
About the NCI Center for Cancer Research
The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, D.C. CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH). Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research. We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV/AIDS. The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies. The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside. Read more about CCR, the benefits of working at CCR and hear from our staff on their CCR experiences.
Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system. The city is a thriving suburban center close to Washington, D.C., and home to many restaurants, retailers and a flourishing arts and entertainment district.