Alberto  Bartesaghi, Ph.D.
Alberto Bartesaghi, Ph.D.
Staff Scientist

Center for Cancer Research
National Cancer Institute

Building 50, Room 4306
Bethesda, MD 20892-8008
301-594-0552

Dr. Bartesaghi's research is devoted to the development of computational imaging technologies to help understand the quantitative aspects of viruses at molecular resolution using cryo-electron tomography. He has developed advanced computational techniques for structure determination of various viral components involved in neutralization and cellular entry of SIV and HIV.

Areas of Expertise
computational imaging

Dr. Bartesaghi's research is devoted to the development of computational imaging technologies to help understand the quantitative aspects of viruses at molecular resolution using cryo-electron tomography. He has developed advanced computational techniques for structure determination of various viral components involved in neutralization and cellular entry of SIV and HIV.

Selected Publications
  1. Harris AK, Bartesaghi A, Milne JL, Subramaniam S.
    J. Virol.. 87: 7191-6, 2013. [ Journal Article ]
  2. Bartesaghi A, Merk A, Borgnia MJ, Milne JL, Subramaniam S.
    Nat. Struct. Mol. Biol.. 20: 1352-7, 2013. [ Journal Article ]
  3. Kuybeda O, Frank GA, Bartesaghi A, Borgnia M, Subramaniam S, Sapiro G.
    J. Struct. Biol.. 181: 116-27, 2013. [ Journal Article ]
  4. Milne JL, Borgnia MJ, Bartesaghi A, Tran EE, Earl LA, Schauder DM, Lengyel J, Pierson J, Patwardhan A, Subramaniam S.
    FEBS J.. 280: 28-45, 2013. [ Journal Article ]
  5. Schauder DM, Kuybeda O, Zhang J, Klymko K, Bartesaghi A, Borgnia MJ, Mayer ML, Subramaniam S.
    Proc. Natl. Acad. Sci. U.S.A.. 110: 5921-6, 2013. [ Journal Article ]

Dr. Alberto Bartesaghi received the B.Sc. and M.Sc. degrees from the Instituto de Ingeniera Electrica, Universidad de la Republica, Montevideo, in 1999 and 2001, respectively, and the Ph.D. degree in Electrical Engineering from the Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, in 2005. He then joined the Laboratory of Cell Biology at the National Cancer Institute, National Institutes of Health, Bethesda, MD in January 2005

Summary

Dr. Bartesaghi's research is devoted to the development of computational imaging technologies to help understand the quantitative aspects of viruses at molecular resolution using cryo-electron tomography. He has developed advanced computational techniques for structure determination of various viral components involved in neutralization and cellular entry of SIV and HIV.

Areas of Expertise
computational imaging

Research

Dr. Bartesaghi's research is devoted to the development of computational imaging technologies to help understand the quantitative aspects of viruses at molecular resolution using cryo-electron tomography. He has developed advanced computational techniques for structure determination of various viral components involved in neutralization and cellular entry of SIV and HIV.

Publications

Selected Publications
  1. Harris AK, Bartesaghi A, Milne JL, Subramaniam S.
    J. Virol.. 87: 7191-6, 2013. [ Journal Article ]
  2. Bartesaghi A, Merk A, Borgnia MJ, Milne JL, Subramaniam S.
    Nat. Struct. Mol. Biol.. 20: 1352-7, 2013. [ Journal Article ]
  3. Kuybeda O, Frank GA, Bartesaghi A, Borgnia M, Subramaniam S, Sapiro G.
    J. Struct. Biol.. 181: 116-27, 2013. [ Journal Article ]
  4. Milne JL, Borgnia MJ, Bartesaghi A, Tran EE, Earl LA, Schauder DM, Lengyel J, Pierson J, Patwardhan A, Subramaniam S.
    FEBS J.. 280: 28-45, 2013. [ Journal Article ]
  5. Schauder DM, Kuybeda O, Zhang J, Klymko K, Bartesaghi A, Borgnia MJ, Mayer ML, Subramaniam S.
    Proc. Natl. Acad. Sci. U.S.A.. 110: 5921-6, 2013. [ Journal Article ]

Biography

Dr. Alberto Bartesaghi received the B.Sc. and M.Sc. degrees from the Instituto de Ingeniera Electrica, Universidad de la Republica, Montevideo, in 1999 and 2001, respectively, and the Ph.D. degree in Electrical Engineering from the Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, in 2005. He then joined the Laboratory of Cell Biology at the National Cancer Institute, National Institutes of Health, Bethesda, MD in January 2005