Congratulations to Dr. Ping Zhang, Dr. Xiang Chen, and Dr. Kylie Walters for receiving CCR Federal Technology Transfer Awards
Congratulations to Dr. Gwen Buel for being selected as a winner of NIH Fellows Award for Research Excellence (FARE) 2019 competition.
We are delighted to have Dr. Dan Shi join the SBL. Dr. Shi is a leading expert in cryoelectron microscopy and microelectron diffraction.
Special congratulations to Dr. Gwen Buel and Dr. Chelsie Conrad for being awarded Sallie Rosen Kaplan Fellowships.
2017 Structural Biology Retreat
The 2017 NCI Structural Biology Retreat was held at beautiful Camp Greentop and featured innovative structural biology approaches to high impact research. Many of our own CCR researchers presented their exciting research and we had the special pleasure of being joined by our distinguished extramural speaker Professor Chris Hill, who shared his groundbreaking findings on protein translocation by the Vps4-Vta1 AAA ATPase. A highlight was our poster sessions, which showcased our talented researchers, with special recognition of Dr. Chelsie Conrad and Dr. Olumide Kayode with Best Poster awards. Special thanks to Dr. Hiroshi Matsuo and Dr. Kylie Walters for organizing, as well as Cindy Castle, Lori Larson, and Team Help for making the day a success.
- Dr. Yun-Xing Wang received the 2017 Director’s Award for his exciting work applying XFEL to riboswitches
- Dr. Yun-Xing Wang was awarded the NCI 2017 Federal Technology Transfer Award
Leadership Evolution at SBL
After receiving a rating of ‘outstanding’ from the SBL site visit review panel, our founding Chief, Dr. R. Andrew Byrd, has decided to step down to focus on his research program. His work is providing foundational insights into allosteric and dynamic mechanisms that control the ubiquitination pathway as well as mechanisms of molecular recognition and regulation of Arfs and Arf-GTPase Activating Proteins at the membrane surface. Andy has been Chief since 1999 and under his leadership, the SBL has grown to its current strength of 4 PIs (all of whom are leaders in their research area), established world class facilities and spearheaded a multidisciplinary approach that has provided powerful mechanistic insights into complex biological process. Dr. Kylie J. Walters will serve as Acting Chief while an international search is conducted to identify Andy’s successor. Kylie joined the SBL as a Senior Investigator in 2013.
2016 Structural Biology Retreat
We had a fantastic 2016 Structural Biology Retreat that was interactive and motivating. The day began with distinguished outside speaker Professor Juli Feigon presenting her integrative structural biology approach to define the Tetrahymena telomerase structure and in turn, make profound mechanistic insights into its function. Yifei Li (from Andy Byrd’s lab) introduced his plans to study a protein complex in a nanodisc to mimic the membrane environment, Kedar Narayan highlighted ongoing efforts in the CMM and its availability to CCR investigators, He Song (from Xinhua Ji’s lab) presented very nice data on a ribonucleoprotein, Kylie Walters presented her ongoing efforts to define new therapeutic sites in the proteasome, Yun-Xing Wang described his success in performing a real time determination of the structure of an intermediate state using XFEL, Di Xia presented his ongoing work to define drug resistance mechanisms for a P-glycoprotein, and newly hired Ping Zhang put forth ambitious plans for her new lab. The poster sessions displayed exciting ongoing projects, with Xiang Chen, Frank Chao, and Sathiya Dharmaiah/Timothy Tran selected for Outstanding Poster Awards. Special thanks to Sergey Tarasov and Kylie Walters for organizing, as well as Cindy Castle, Lori Larson and Team Help for making the day a success.
MOVING: SBL will be relocating to the ATRF building in Frederick, fall 2016, to make way for renovation of Building 538. NMR facilities will remain operational adjacent to Bldg. 538 and SBL looks forward to returning to new labs in 2018.
2016 Statdman Tenure-track PI
The SBL is pleased to announce the arrival of Dr. Ping Zhang as a Stadtman Tenure-Track PI. Ping joined the SBL in August 2016, and she will initiate a research program combining cryoEM and crystallography in the study of complexes regulating kinase activity. The group has already recruited two new postdoctoral fellows. Please contact Ping Zhang if you are interested in joining her research group.
2015 Structural Biology Retreat
Dr. Kylie Walters organized the retreat in October 2015, bringing together PIs with interest in structural biology from the Frederick campus (both Ft. Detrick and ATRF sites) and the Bethesda campus. It was an exciting day of talks and posters, and it will become an annual event. Please watch for dates and join in!
Structural Biology Retreat, October 2015, brings together researchers from multiple disciplines across the Frederick and Bethesda campuses of NCI.