Pediatric-Oncology-Branch
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Feasibility and Preliminary Efficacy of an Enhanced Mindfulness Intervention for Children with High Grade Brain Tumors and Their Caregivers.
Open - Not yet Recruiting Protocol Summary Not Yet Available. Call Referral Contact.NCI Protocol ID NCI-18-C-0080Investigator Staci Martin Peron, Ph.D. -
Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults with Refractory Sarcomas, Wilms Tumor, and Other Rare Tumors
Open - Not yet RecruitingNCI Protocol ID NCI-18-C-0062Investigator Brigitte C. Widemann, M.D. -
A Phase IB/II Single-arm Study of M7824 (MSB0011359C) in Combination with Gemcitabine in Adults with Previously Treated Advanced Adenocarcinoma of the Pancreas
Open - RecruitingNCI Protocol ID NCI-18-C-0061Investigator Udo Rudloff, M.D., Ph.D. -
Phase 1 Dose Escalation Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Open - RecruitingNCI Protocol ID NCI-18-C-0059Investigator Nirali N. Shah, M.D., MHSc -
Long Term Follow-up of Subjects Exposed to NY-ESO-1c259 T, a Genetically Engineered NY-ESO-1 Specific T Cell Receptor
Open - Not yet Recruiting Protocol Summary Not Yet Available. Call Referral Contact.NCI Protocol ID NCI-18-C-0038Investigator John W. Glod, M.D. -
A Phase 2 Study of Inotuzumab Ozogamicin (NSC# 772518, IND#133494) in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)
Open - Not yet RecruitingNCI Protocol ID NCI-18-C-0026Investigator Nirali N. Shah, M.D., MHSc -
CC-4047-BRN-001A Phase 2 Clinical Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults with Recurrent or Progressive Primary Brain Tumors
Open - RecruitingNCI Protocol ID NCI-17-C-0175Investigator Katherine E. Warren, M.D. -
A Phase II Study of Selumetinib (AZD6244) for the Treatment of Advanced Pancreas Cancer harboring KRAS G12R Mutations
Open - RecruitingNCI Protocol ID NCI-17-C-0144Investigator Udo Rudloff, M.D., Ph.D. -
Leukapheresis for CAR-Therapy Manufacturing
Open - RecruitingNCI Protocol ID NCI-17-C-0137Investigator Nirali N. Shah, M.D., MHSc -
A Phase II Trial of the DNA Methyl Transferase Inhibitor, SGI-110(Guadecitabine), in Children and Adults with Wild Type GIST, Pheochromocytoma and Paraganglioma Associated with Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer
Open - RecruitingNCI Protocol ID NCI-17-C-0088Investigator John W. Glod, M.D. -
A Phase 1, Open-label, Dose Escalation Study of MGA271 in Pediatric Patients with B7-H3-Expressing Relapsed or Refractory Solid Tumors
Open - RecruitingNCI Protocol ID NCI-17-C-0085Investigator Rosandra N. Kaplan, M.D. -
A Phase II Trial of the Mitogen Activated Protein Kinase Kinase (MEK1/2) inhibitor Selumetinib (AZD6244 hydrogen sulfate) in Patients with Neurofibromatosis Type 1 (NF1) related Gastrointestinal Stomal Tumors (GIST)
Open - RecruitingNCI Protocol ID NCI-17-C-0084Investigator Brigitte C. Widemann, M.D. -
A Phase I/II Trial of the Insulin-like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination with the Src Family Kinase (SFK) Inhibitor Dasatinib in Patients with Embryonal and Alveolar Rhabdomyosarcoma
Open - RecruitingNCI Protocol ID NCI-17-C-0049Investigator Christine M. Heske, M.D. -
A Pilot Study of Vincristine Sulfate Liposome Injection (Marqibo®) in Combination with UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults with Relapse of Acute Lymphoblastic Leukemia
Open - RecruitingNCI Protocol ID NCI-17-C-0028Investigator Nirali N. Shah, M.D., MHScShare this trial: Referral ContactsContact Name Phone Number Nirali Shah, M.D., MHSc. (301) 451-0390 -
Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine Glioma
Open - RecruitingNCI Protocol ID NCI-16-C-0097Investigator Katherine E. Warren, M.D. -
Phase II Trial of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Adults with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas
Open - RecruitingNCI Protocol ID NCI-16-C-0043Investigator Brigitte C. Widemann, M.D.Share this trial: Referral ContactsContact Name Phone Number Amanda Carbonell 301.496.0486 Trish Whitcomb 301.435.6836 -
Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals with Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (PNs)
Open - RecruitingNCI Protocol ID NCI-15-C-0195Investigator Pamela L. Wolters, Ph.D. -
Acceptance and Commitment Training for Adolescents and Adults with Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic PainA Phase III Clinical Trial
Open - RecruitingNCI Protocol ID NCI-15-C-0142Investigator Staci Martin Peron, Ph.D. -
Phase I/II Study of Nivolumab (IND#124729) in Children, Adolescents, and Young Adults with Recurrent or Refractory Solid Tumors as a Single Agent and in Combination with Ipilimumab
Open - RecruitingNCI Protocol ID NCI-15-C-0101Investigator Brigitte C. Widemann, M.D. -
Phase I Dose Escalation Study of Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults with Recurrent or Refractory CD22-expressing B Cell Malignancies
Open - RecruitingNCI Protocol ID NCI-15-C-0029Investigator Nirali N. Shah, M.D., MHSc -
Follow-Up Evaluation for Gene-Therapy Related Delayed Adverse Events after Participation in Pediatric Oncology Branch Clinical Trials
Open - Enrolling by Invitation OnlyNCI Protocol ID NCI-15-C-0028Investigator Terry J. Fry, M.D.Share this trial: Referral ContactsContact Name Phone Number Cindy Delbrook 301.496.9454 Donna Bernstein 301.435.7804 -
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1Clinical, Histopathologic, and Genomic Analysis
Open - RecruitingNCI Protocol ID NCI-14-C-0163Investigator Brigitte C. Widemann, M.D. -
Phase 1 Study of a Combination of the PARP inhibitor, Niraparib and Temozolomide in Patients with Previously Treated, incurable Ewing's Sarcoma
Open - RecruitingNCI Protocol ID NCI-14-C-0129Investigator John W. Glod, M.D. -
A Randomized Controlled Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated with Cranial Radiation for Brain Tumors
Open - RecruitingNCI Protocol ID NCI-14-C-0116Investigator Pamela L. Wolters, Ph.D. -
An Exploratory Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults with Cancer and Other Life Threatening Illnesses
Open - RecruitingNCI Protocol ID NCI-14-C-0079Investigator Lori Wiener, Ph.D., DCSW, LCSW-C -
Understanding the Perceived Influence of Childhood Cancer on the Parents' Marital/partner RelationshipA Descriptive Study
Open - RecruitingNCI Protocol ID NCI-12-C-0206Investigator Lori Wiener, Ph.D., DCSW, LCSW-C -
Longitudinal Assessment and Natural History Study of Children and Adults with MEN2A or MEN2B with or without Medullary Thyroid Carcinoma
Open - RecruitingNCI Protocol ID NCI-12-C-0178Investigator John W. Glod, M.D. -
Validation of the English Version of the Pain Interference Index and the Pain Rating Scale in Children, Adolescents, and Young Adults with Chronic Illness and Their Parents
Open - RecruitingNCI Protocol ID NCI-12-C-0160Investigator Staci Martin Peron, Ph.D. -
Phase I Study of T Cells Expressing an Anti-CD19 Chimeric Receptor in Children and Young Adults with B Cell Malignancies
Open - For Data/Specimen AnalysisNCI Protocol ID NCI-12-C-0112Investigator Terry J. Fry, M.D. -
A Phase 1 and Phase II and Retreatment Study of AZD6244 for Recurrent or Refractory Pediatric Low Grade Glioma
Open - RecruitingNCI Protocol ID NCI-11-C-0191Investigator Katherine E. Warren, M.D. -
A Phase I/II Study of the Mitogen Activated Protein Kinase Kinase (MEK) 1 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Children with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)
Open - RecruitingNCI Protocol ID NCI-11-C-0161Investigator Brigitte C. Widemann, M.D. -
A Pilot Study of Genetically Engineered NY-ESO-1 Specific (c259) T cells in HLA-A2+ Patients with Synovial Sarcoma
Open - RecruitingNCI Protocol ID NCI-11-C-0113Investigator John W. Glod, M.D. -
Related and Unrelated Donor Hematopoietic Stem Cell Transplant for DOCK8 Deficiency
Open - RecruitingNCI Protocol ID NCI-10-C-0174Investigator Nirali N. Shah, M.D., MHSc -
Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies
Open - RecruitingNCI Protocol ID NCI-10-C-0086Investigator Rosandra N. Kaplan, M.D.Share this trial: Referral ContactsContact Name Phone Number -
Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1
Open - RecruitingNCI Protocol ID NCI-08-C-0079Investigator Brigitte C. Widemann, M.D. -
An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System Tumors
Open - RecruitingNCI Protocol ID NCI-06-C-0219Investigator Katherine E. Warren, M.D. -
Hematologic Malignancy Biology Study
Open - Enrolling by Invitation OnlyNCI Protocol ID NCI-04-C-0102Investigator Terry J. Fry, M.D. -
A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)
Open - RecruitingNCI Protocol ID NCI-03-C-0278Investigator Katherine E. Warren, M.D.