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Frank I. Lin, M.D.

Frank I. Lin, M.D.

  • Center for Cancer Research
  • National Cancer Institute
Molecular Imaging Branch

RESEARCH SUMMARY

Dr. Lin is a board-certified physician in the fields of medical oncology and nuclear medicine. Dr. Lin's research interest is in the use of systemic, targeted radionuclides or conjugates as a treatment modality for cancer, and he is head of the Targeted Radionuclide Therapy Section of the Molecular Imaging Branch at NCI. Selected as a Lasker Clinical Research Scholar in 2016, Dr. Lin leads several pre-clinical investigations of radionuclide therapy agents as well as being the principal or associate investigator on a number of clinical trials at the NIH involving radionuclide therapy. Dr. Lin is particularly interested in the development and clinical translation of novel alpha particle and Auger electron-emitting radionuclides as targeted therapy for cancer.

Areas of Expertise

Targeted Radionuclide Therapy
Alpha Particle-Emitting Radionuclides
Nuclear Medicine
Positron Emission Tomography (PET)

Information for Patients

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Publications

Selected Recent Publications

Continuing Medical Education: Systemic Radionuclide Therapy of Pheochromocytoma/Paraganglioma

Carrasquillo J, et al. [Senior author]
Journal of Nuclear Medicine and Molecular Imaging . [ Journal Article ]

In vitro and in vivo comparison of 3,2-HOPO versus DFO-based chelation of zirconium-89 to the anti-mesothelin antibody anetumab

Roy J, et al. [Senior author]
Cancer Biotherapy and Radiopharmaceuticals . 2017. [ Journal Article ]

Utility of 18F-fluoroestradiol (18F-FES) PET/CT imaging as a pharmacodynamic marker in patients with refractory estrogen receptor-positive solid tumors receiving Z-endoxifen therapy

Lin FI., Mena E., Lindenberg L., Adler S., Ton A., et al
Eur J Nucl Med Mol Imaging. 44(3): 500-508, 2017. [ Journal Article ]

Case Report: Primary Hypothyroidism Associated with Lutetium 177-DOTATATE Therapy for Metastatic Paraganglioma

Gubbi S, et al. [Senior author]
Frontiers in Endocrinology-Cancer Endocrinology. Jan 12: 2021. [ Journal Article ]

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Alumni

Jyoti Roy, Ph.D.
Jyoti Roy, Ph.D.
2017-2021
Research Fellow/ Visiting Fellow

Team

Postdoctoral Fellow (Visiting)
Bruna Fernandes, Ph.D.